AMINOMETHYLBENZOIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H9NO2
Molecular Weight	151.1626
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NCC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=QCTBMLYLENLHLA-UHFFFAOYSA-N

InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)

HIDE SMILES / InChI

Description

Aminomethylbenzoic acid (or p-aminomethylbenzoic acid, or PAMBA) an antifibrinolytic agent. This drug has been used for the treatment of internal hemorrhage during chronic disseminated intravascular coagulation.

Approval Year

PubMed

Show entries

Title	Date	PubMed
[Hematuria due to increased urokinase activity. Its successful treatment with p-aminomethylbenzoic acid (PAMBA)].	1965 Oct 8	5898922
The Cardiovascular Society in the GDR (German Democratic Republic).	2002	12436747
Novel fragmentation pathway for CID of (b(n) - 1 + Cat)+ ions from model, metal cationized peptides.	2005 Aug	15990332
Activation of vagal afferents in the rat duodenum by protein digests requires PepT1.	2005 Jun	15930458
Radiosynthesis and evaluation of [11C]BTA-1 and [11C]3'-Me-BTA-1 as potential radiotracers for in vivo imaging of beta-amyloid plaques.	2007	18084683

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Patents

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Name

Type

Language

AMINOMETHYLBENZOIC ACID

Systematic Name

English

NSC-41629

Code

English

TRANEXAMIC ACID RELATED COMPOUND D [USP IMPURITY]

Common Name

English

Aminomethylbenzoic acid [WHO-DD]

Common Name

English

PAMBA

Common Name

English

Showing 1 to 5 of 9 entries

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Classification Tree

Code System

Code

Amino acids

WHO-VATC

QB02AA03

Amino acids

WHO-ATC

B02AA03

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Code System

Code

Type

Description

EVMPD

SUB12854MIG

PRIMARY

WIKIPEDIA

AMINOMETHYLBENZOIC ACID

PRIMARY

PUBCHEM

65526

PRIMARY

ECHA (EC/EINECS)

200-297-9

PRIMARY

ChEMBL

CHEMBL328875

PRIMARY

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SALT/SOLVATE (PARENT)


					MVW2TZW37D

4-(Aminomethyl)benzoic acid hydrochloride

SUBSTANCE RECORD


					68WG9JKC7L

AMINOMETHYLBENZOIC ACID