NITRAMISOLE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H11N3O2S.ClH
Molecular Weight	285.75
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[O-][N+](=O)C1=CC=CC(=C1)C2CN3CCSC3=N2

InChI

InChIKey=ILUWATRNRIWZJO-UHFFFAOYSA-N

InChI=1S/C11H11N3O2S.ClH/c15-14(16)9-3-1-2-8(6-9)10-7-13-4-5-17-11(13)12-10;/h1-3,6,10H,4-5,7H2;1H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7397601 | https://www.ncbi.nlm.nih.gov/pubmed/7147006

Nitramisole, an imidazothiazole derivative, is an anthelmintic. Nitramisole was effective against migrating Strongylus vulgaris larvae in ponies. Treatment of infected ponies with Nitramisole resulted both a clinical and radical cure.

Approval Year

PubMed

Title	Date	PubMed
Evaluation of pyrantel pamoate, nitramisole and avermectin B1a against migrating Strongylus vulgaris larvae.	1980 Jan	7397601
In vitro activity of anthelmintic drugs and biologically active substances on Breinlia booliati.	1982 Jun	7147006
[Observation on therapeutic effect of medicinal moxa stick moxibustion for treatment of tinea pedis].	2009 Jul	19835120

Patents

Sample Use Guides

In Vivo Use Guide

Ponies were infected, each with 2000 infective Strongylus vulgaris larvae. Nitramisole was administered on day 7 to one group via a stomach tube at the rate of 8 mg/kg.

Route of Administration: Intragastric

Name

Type

Language

NITRAMISOLE HYDROCHLORIDE

Official Name

English

NITRAMISOLE HYDROCHLORIDE [USAN]

Common Name

English

R-29860

Code

English

(±)-2,3,5,6-TETRAHYDRO-6-(M-NITROPHENYL)-IMIDAZO(2,1-B)THIAZOLE MONOHYDROCHLORIDE

Systematic Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(3-NITROPHENYL)-, MONOHYDROCHLORIDE, (±)-

Common Name

English

R 29,860

Code

English

NITRAMISOLE HCL

Common Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(3-NITROPHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250