NITRAMISOLE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H11N3O2S.ClH
Molecular Weight	285.75
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.[O-][N+](=O)C1=CC=CC(=C1)C2CN3CCSC3=N2

InChI

InChIKey=ILUWATRNRIWZJO-UHFFFAOYSA-N

InChI=1S/C11H11N3O2S.ClH/c15-14(16)9-3-1-2-8(6-9)10-7-13-4-5-17-11(13)12-10;/h1-3,6,10H,4-5,7H2;1H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7397601 | https://www.ncbi.nlm.nih.gov/pubmed/7147006

Nitramisole, an imidazothiazole derivative, is an anthelmintic. Nitramisole was effective against migrating Strongylus vulgaris larvae in ponies. Treatment of infected ponies with Nitramisole resulted both a clinical and radical cure.

Approval Year

PubMed

Title	Date	PubMed
[Observation on therapeutic effect of medicinal moxa stick moxibustion for treatment of tinea pedis].	2009-07	19835120
In vitro activity of anthelmintic drugs and biologically active substances on Breinlia booliati.	1982-06	7147006
Evaluation of pyrantel pamoate, nitramisole and avermectin B1a against migrating Strongylus vulgaris larvae.	1980-01	7397601

Patents

Sample Use Guides

In Vivo Use Guide

Ponies were infected, each with 2000 infective Strongylus vulgaris larvae. Nitramisole was administered on day 7 to one group via a stomach tube at the rate of 8 mg/kg.

Route of Administration: Intragastric

Name

Type

Language

NITRAMISOLE HYDROCHLORIDE

Official Name

English

R 29,860

Preferred Name

English

NITRAMISOLE HYDROCHLORIDE [USAN]

Common Name

English

R-29860

Code

English

(±)-2,3,5,6-TETRAHYDRO-6-(M-NITROPHENYL)-IMIDAZO(2,1-B)THIAZOLE MONOHYDROCHLORIDE

Systematic Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(3-NITROPHENYL)-, MONOHYDROCHLORIDE, (±)-

Common Name

English

NITRAMISOLE HCL

Common Name

English

IMIDAZO(2,1-B)THIAZOLE, 2,3,5,6-TETRAHYDRO-6-(3-NITROPHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250