Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H8N2O2 |
Molecular Weight | 152.1506 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C=C(C=CC1=O)C(N)=O
InChI
InChIKey=JLQSXXWTCJPCBC-UHFFFAOYSA-N
InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11)
Approval Year
PubMed
Title | Date | PubMed |
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Excretion of tryptophan-niacin metabolites by young men: effects of tryptophan, leucine, and vitamin B6 intakes. | 1980 Oct |
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Quantitation of urinary niacin metabolites by reversed-phase liquid chromatography. | 1982 Nov |
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The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production. | 2001 Apr |
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[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats]. | 2001 Jun |
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Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure. | 2002 Feb |
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Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats. | 2002 Jun |
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Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee. | 2002 Oct 15 |
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The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells. | 2005 |
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Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status. | 2005 Mar 25 |
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Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | 2007 Jun |
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Are so-called uremic toxins always toxic? | 2008 Jan |
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Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | 2010 May |
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Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | 2010 Oct |
Patents
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DTXSID70220374
Created by
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68139USC7W
Created by
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N1-Methyl-2-pyridone-5-carboxamide
Created by
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27410
Created by
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701-44-0
Created by
admin on Sat Dec 16 08:58:57 GMT 2023 , Edited by admin on Sat Dec 16 08:58:57 GMT 2023
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69698
Created by
admin on Sat Dec 16 08:58:57 GMT 2023 , Edited by admin on Sat Dec 16 08:58:57 GMT 2023
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PARENT (METABOLITE)
SUBSTANCE RECORD