PHENOBUTIODIL

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H9I3O3
Molecular Weight	557.8901
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(OC1=C(I)C=C(I)C=C1I)C(O)=O

InChI

InChIKey=VYAGDYWTCWDKIS-UHFFFAOYSA-N

InChI=1S/C10H9I3O3/c1-2-8(10(14)15)16-9-6(12)3-5(11)4-7(9)13/h3-4,8H,2H2,1H3,(H,14,15)

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/862320 / Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 961, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://www.ncbi.nlm.nih.gov/pubmed/13504056 | https://www.drugfuture.com/chemdata/Phenobutiodil.html

Phenobutiodil was used as the contrast medium in radiology. As a diagnostic aid in cholecystography. Conjugated phenobutiodil (Biliodyl) in the small and large bowel can be recognized by its fine, homogeneous appearance.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Recent triiodinated contrast media for oral cholecystocholangiography].	1985-02	3155821
The significance of conjugated phenobutiodil (biliodyl) in the intestine in the absence of gallbladder opacification a preliminary assessment.	1977-05	862320
[Clinical studies with the oral billary contrast medium baygnostil].	1959-12-05	13851868
[Experiences with the triiodated oral gallbladder contrast medium baygnostil].	1959-01-30	13626705
[Baygnostil, a new triiodized oral biliary contrast medium].	1958-12	13608798
[Use of the oral contrast medium baygnostil in cholecystography].	1958-11-08	13612614
[Oral cholecystography with baygnostil].	1957-12-13	13504056
[Baygnostil, a new contrast medium in cholecystography, & its practical trial].	1957-11-02	13492947
A comparative trial of telepaque and biliodyl in 50 cases.	1957-07	13436756

Sample Use Guides

In Vivo Use Guide

Single dose of 3 g (six tablets)

Route of Administration: Oral

Name

Type

Language

PHENOBUTIODIL [MI]

Preferred Name

English

PHENOBUTIODIL

Official Name

English

Phenobutiodil [WHO-DD]

Common Name

English

2-(2,4,6-TRIIODOPHENOXY)BUTYRIC ACID

Systematic Name

English

phenobutiodil [INN]

Common Name

English

Code System Code Type Description

INN

473