PSEUDOAKUAMMIGINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H26N2O3
Molecular Weight	366.4534
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@H]3\C(CN1CC[C@@]45C6=CC=CC=C6N(C)[C@@]24OC[C@@]35C(=O)OC)=C/C

InChI

InChIKey=HAGBWVNSVWLTKY-ZFWLQQAWSA-N

InChI=1S/C22H26N2O3/c1-4-14-12-24-10-9-21-15-7-5-6-8-17(15)23(2)22(21)18(24)11-16(14)20(21,13-27-22)19(25)26-3/h4-8,16,18H,9-13H2,1-3H3/b14-4-/t16-,18-,20-,21-,22+/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Potency
Mu-type opioid receptor 61 Target ID: P97266 Gene ID: NA Gene Symbol: OPRM1 Target Organism: Cavia porcellus (Guinea pig) Sources: https://www.ncbi.nlm.nih.gov/pubmed/9683021	Interacts 323	0.89 µM [Ki]
Kappa-type opioid receptor 60 Target ID: P41144 Gene ID: 1.00135584E8 Gene Symbol: OPRK1 Target Organism: Cavia porcellus (Guinea pig) Sources: https://www.ncbi.nlm.nih.gov/pubmed/9683021	Interacts 323	0.92 µM [Ki]
UniProtKB - A0A286XTF2 (A0A286XTF2_CAVPO) 1 Target ID: UniProtKB - A0A286XTF2 (A0A286XTF2_CAVPO) Sources: https://www.ncbi.nlm.nih.gov/pubmed/9683021	Interacts 323	5.95 µM [Ki]

PubMed

Title	Date	PubMed
Opioid activity of alkaloids extracted from Picralima nitida (fam. Apocynaceae).	1998 May 29	9683021
Current progress in the chemistry and pharmacology of akuammiline alkaloids.	2003 Sep	12871110

Name

Type

Language

PSEUDOAKUAMMIGINE

Common Name

English

DEOXYAKUAMMINE

Common Name

English

2H,12H-12A,2,7A-(EPOXYETHANYLYLIDENE)INDOLO(2,3-A)QUINOLIZINE-15-CARBOXYLIC ACID, 3-ETHYLIDENE-1,3,4,6,7,12B-HEXAHYDRO-12-METHYL-, METHYL ESTER, (2S,3E,7AS,12AS,12BS,15R)-

Systematic Name

English

AKUAMMINE, 10-DEOXY-

Common Name

English

NSC-381082

Code

English

.OMEGA.-AKUAMMIGINE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID701336401