AGANODINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H10Cl2N4
Molecular Weight	245.109
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AGANODINE

Structure Search

SMILES

NC(=N)NN1CC2=C(Cl)C=CC(Cl)=C2C1

InChI

InChIKey=DFKHOVYSCCPSHR-UHFFFAOYSA-N

InChI=1S/C9H10Cl2N4/c10-7-1-2-8(11)6-4-15(3-5(6)7)14-9(12)13/h1-2H,3-4H2,(H4,12,13,14)

HIDE SMILES / InChI

Description
Sources: https://www.researchgate.net/publication/294210987_Potential_mechanisms_involved_in_aganodine-induced_ocular_hypotension

Aganodine, an imidazoline/ alpha-2 receptor agonist, can lower intraocular pressure in the sympathetic neurons of the eye and possibly in the central nervous system.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Presynaptic imidazoline receptors and non-adrenoceptor [3H]-idazoxan binding sites in human cardiovascular tissues.	1997 Sep	9298527

Name

Type

Language

AGANODINE

Official Name

English

(4,7-DICHLORO-2-ISOINDOLINYL)GUANIDINE

Systematic Name

English

aganodine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29709

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

Code System Code Type Description

PUBCHEM

176878

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

NCI_THESAURUS

C74229

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

EPA CompTox

DTXSID60235775

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

ChEMBL

CHEMBL2105912

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

EVMPD

SUB05284MIG

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

CAS

86696-87-9

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

SMS_ID

100000087708

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

FDA UNII

670P9AQR46

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

INN

5488

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

WIKIPEDIA

Aganodine

Created by admin on Fri Dec 15 16:19:52 GMT 2023 , Edited by admin on Fri Dec 15 16:19:52 GMT 2023

PRIMARY

ACTIVE MOIETY


					670P9AQR46

AGANODINE