DESOXYCORTICOSTERONE GLUCOSIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H40O8
Molecular Weight	492.6017
Optical Activity	UNSPECIFIED
Defined Stereocenters	11 / 11
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DESOXYCORTICOSTERONE GLUCOSIDE

Structure Search

SMILES

[H][C@@]12CC[C@H](C(=O)CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@]1(C)CC[C@@]4([H])[C@@]2([H])CCC5=CC(=O)CC[C@]45C

InChI

InChIKey=SMSMUZPFFJLROV-LARVYCNESA-N

InChI=1S/C27H40O8/c1-26-9-7-15(29)11-14(26)3-4-16-17-5-6-19(27(17,2)10-8-18(16)26)20(30)13-34-25-24(33)23(32)22(31)21(12-28)35-25/h11,16-19,21-25,28,31-33H,3-10,12-13H2,1-2H3/t16-,17-,18-,19+,21+,22+,23-,24+,25+,26-,27-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12990671

Desoxycorticosterone glucoside was studied in human in 1950th, where was shown, that intravenous injection of this compound did not narrow arterial-cerebral venous glucose difference. In no instance did cerebral venous blood sugar content surpass or approach arterial levels.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Some biological properties of desoxycorticosterone glucoside.	1950 Jan	15405778
[The formation of aseptic corneal abscesses plotted as a function of monoiodoacetic acid and desoxycorticosterone glucoside].	1951	14936954
Effect of intravenous injections of desoxycorticosterone glucoside upon blood glucose of adrenalectomized dogs.	1951 Dec	14912057
Effect of desoxycorticosterone glucoside upon cerebral blood flow and metabolism of human subjects.	1951 Feb	14814212

Sample Use Guides

In Vivo Use Guide

Single injection of 50 mg of desoxycorticosterone glucoside.

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Name

Type

Language

DESOXYCORTICOSTERONE GLUCOSIDE

Common Name

English

DESOXYCORTONE GLUCOSIDE

Common Name

English

11-DEOXYCORTICOSTERONE 21-GLUCOSIDE

Common Name

English

PREGN-4-ENE-3,20-DIONE, 21-(.BETA.-D-GLUCOPYRANOSYLOXY)-

Systematic Name

English

11-DEOXYCORTICOSTERONE GLUCOSIDE

Common Name

English

DEOXYCORTICOSTERONE .BETA.-D-GLUCOPYRANOSIDE

Common Name

English

DEOXYCORTICOSTERONE 21-GLUCOSIDE

Common Name

English

CORTICOSTERONE, DEOXY-, .BETA.-D-GLUCOPYRANOSIDE

Systematic Name

English

DEOXYCORTICOSTERONE GLUCOSIDE

Common Name

English

Code System Code Type Description

CAS

4319-56-6