U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Details

Stereochemistry ACHIRAL
Molecular Formula C2H8N2
Molecular Weight 60.0983
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Ethylenediamine

SMILES

NCCN

InChI

InChIKey=PIICEJLVQHRZGT-UHFFFAOYSA-N
InChI=1S/C2H8N2/c3-1-2-4/h1-4H2

HIDE SMILES / InChI
Ethylenediamine is a strongly basic amine useful as a building block in chemical synthesis. It is used as a solvent to dissolve proteins such as albumins, casein and in medicine to stabilize aminophylline when used in injections. Ethylenediamine is used in manufacture of chelating agents (EDTA), epoxy curing agents, dimethylolethylene-urea resins, emulsifying agents, textile lubricants, antifreeze inhibitor. It is also involved in the manufacture of many industrial chemicals and forms derivatives with carboxylic acids, nitriles, alcohols, alkylating agents, carbon disulfide, aldehydes and ketones. It is a basic building block to prepare heterocyclic compound such as imidazolidines.

Approval Year

PubMed

PubMed

TitleDatePubMed
Kinetics and mechanisms of EDTA photocatalytic degradation with TiO2.
2001
[Effect of Na2H2EDTA on the viability of rats' organism during hypothermia].
2001
Non-detection of Chlamydia species in carotid atheroma using generic primers by nested PCR in a population with a high prevalence of Chlamydia pneumoniae antibody.
2001
Biodegradable biocomposite non-woven matrices based on PDLLA- and elastin-solubilized proteins/elastin.
2001
Use of a new HemoCue system for measuring haemoglobin at low concentrations.
2001 Apr
Prenatal HLA typing of uncultured amniocytes prior to the collection of related allogeneic cord blood.
2001 Aug
Speciation of rare earth elements in soil by sequential extraction then HPLC coupled with visible and ICP-MS detection.
2001 Aug
Hydrogen-bonded adducts of ferrocene-1,1'-diylbis(diphenylmethanol): monomeric and dimeric 1:1 adducts with 1,2-bis(4-pyridyl)ethane and 1,2-diaminoethane.
2001 Aug
[H3N(CH2)2NH3]0.5[BePO4], a beryllophosphate analogue of aluminosilicate zeolite gismondine.
2001 Aug
Biodegradability of ethylenediamine-based complexing agents and related compounds.
2001 Aug
Synthesis and structure of [K(+)-(2,2)diaza-[18]-crown-6][K3Ge9]-2ethylenediamine: stabilization of the two-dimensional layer (2)(infinity)[K3Ge9(1-)].
2001 Aug 27
Secretion of a trypsin-like thiol protease by a new keratinolytic strain of Bacillus licheniformis.
2001 Dec 18
Yield and post-yield behavior of mussel byssal thread: a self-healing biomolecular material.
2001 Fall
Potential energy surface crossings and the mechanistic spectrum for intramolecular electron transfer in organic radical cations.
2001 Jan 31
[Effect of calcium ion level in blood on physiological functions in rat subjected to immersion hypothermia].
2001 Jul
Preparation of a ribonucleic acid-(polyamidoamine)-(zirconia-urea-formaldehyde resin) high-performance liquid affinity chromatographic stationary phase.
2001 Jul
Tetranuclear mixed-metal M(II)2Cu(II)2 complexes derived from a phenol-based macrocyclic ligand having two N(amine)2O2 and two N(imine)2O2 metal-binding sites.
2001 Jul 16
Rabbit M cells and dome enterocytes are distinct cell lineages.
2001 Jun
Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins.
2001 Jun
Chemoenzymatic synthesis of sucrose-containing aromatic polymers.
2001 Mar 5
Catalysis and inhibition of ligand substitution in palladium(II) square-planar complexes: effects of DNA.
2001 Mar 7
[Effect of alpha-lipoic acid preparations on bilirubin and transferrin levels and ferritin iron and transferrin iron content].
2001 Mar-Apr
A three-dimensional porous framework complex, poly[[bis(ethylenediamine)copper(II)] [potassium hexacyanocobalt(III)]].
2001 Nov
Plane-wave density functional theoretic study of formation of clay-polymer nanocomposite materials by self-catalyzed in situ intercalative polymerization.
2001 Nov 28
Gold-gold interactions as crystal engineering design elements in heterobimetallic coordination polymers.
2001 Nov 5
Polar nitrogen compounds and their behaviour in the drinking water treatment process.
2001 Oct
Predictive value of chromatin decondensation in vitro on fertilization rate after intracytoplasmic sperm injection (ICSI).
2001 Oct
The effect of pH and concentration upon aggregation transitions in aqueous solutions of poloxamine T701.
2001 Oct 23
Inhibition of cancer cell growth by ruthenium(II) arene complexes.
2001 Oct 25
Layered cobalt hydroxysulfates with both rigid and flexible organic pillars: synthesis, structure, porosity, and cooperative magnetism.
2001 Oct 31
Design of oxytocin antagonists, which are more selective than atosiban.
2001 Sep
Effect of modification of the carboxyl groups of the sialic acid binding lectin from bullfrog (Rana catesbeiana) oocyte on anti-tumor activity.
2001 Sep
Aminoethylethanolamine: a new allergen in cosmetics?
2001 Sep
Syntheses, vibrational spectra, and theoretical studies of the adamantanoid Sn(4)Ch(10)(4-) (Ch = Se, Te) anions: X-ray crystal structures of [18-crown-6-K](4)[Sn4Se10]*5en and [18-crown-6-K](4)[Sn4Te10]*3en*2THF.
2001 Sep 10
Utilization of quinolone drugs as monomers: characterization of the synthesis reaction products for poly(norfloxacin diisocyanatododecane polycaprolactone).
2001 Spring
[Occupational asthma due to amines].
2002 Feb
Experimental studies on the nature of bonding of DNA*bipyridyl-(ethylenediamine)platinum(II) and DNA*netropsin complexes in solution and oriented wet-spun films.
2002 Feb
Bis(ethylenediamine)copper(II) bis(O,O'-diethyl dithiophosphate).
2002 Feb
Molecular characteristics of glnA linked mutations in the nitrogen-fixing cyanobacterium Nostoc muscorum.
2002 Feb
Schiff bis bases: analytical reagents. II. Spectrophotometric determination of manganese from pharmaceutical forms.
2002 Feb 1
c-erbB-2 is not a major factor in the development of colorectal cancer.
2002 Feb 12
Structure-directing coordination template effect of ethylenediamine in formations of ZnS and ZnSe nanocrystallites via solvothermal route.
2002 Feb 25
Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide.
2002 Jan
Galactosylated alginate as a scaffold for hepatocytes entrapment.
2002 Jan
Development of preparation methods for and insights obtained from atomic force microscopy of fluid spaces in cortical bone.
2002 Jan-Feb
Direct synthesis of peptides on convective interaction media monolithic columns for affinity chromatography.
2002 Jan-Feb
Three different bonding modes of cyano groups in the coordination polymer [Cu(en)2(H(2)O)][Cu(en)(2)Ni(2)Cu(2)(CN)(10)] x 2H(2)O (en is 1,2-diaminoethane).
2002 Mar
Designed self-assembly of molecular necklaces.
2002 Mar 13
Role of magnesium in nucleotide exchange on the small G protein rac investigated using novel fluorescent Guanine nucleotide analogues.
2002 Mar 19
[Ph(2)Bi-(Ge(9))-BiPh(2)](2-): a deltahedral Zintl ion functionalized by exo-bonded ligands.
2002 Mar 20
Patents
Name Type Language
Ethylenediamine
EP   HSDB   II   MART.   MI   USP   WHO-DD  
Systematic Name English
EDAMINE
INN  
INN  
Preferred Name English
ETHYLENEDIAMINE [MART.]
Common Name English
ETHYLENE DIAMINE
Common Name English
ETHYLENEDIAMINE [HSDB]
Common Name English
ETHYLENEDIAMINE [II]
Common Name English
ETHYLENEDIAMINE [EP MONOGRAPH]
Common Name English
Ethylenediamine [WHO-DD]
Common Name English
1,2-DIAMINOETHANE
Systematic Name English
1,2-ETHANEDIAMINE
Systematic Name English
ETHYLENEDIAMINE [JAN]
Common Name English
edamine [INN]
Common Name English
ETHYLENEDIAMINE [USP MONOGRAPH]
Common Name English
PB05721
Code English
ETHYLENEDIAMINE [MI]
Common Name English
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Common Name English
PB-05721
Code English
Classification Tree Code System Code
NDF-RT N0000185508
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
EPA PESTICIDE CODE 4205
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
CFR 21 CFR 173.320
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
Code System Code Type Description
RXCUI
4158
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY RxNorm
INN
7141
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
NDF-RT
N0000171131
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY Allergens [Chemical/Ingredient]
MERCK INDEX
m5119
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY Merck Index
DRUG BANK
DB14189
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
ChEMBL
CHEMBL816
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
CONCEPT Industrial Aid
PUBCHEM
3301
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
FDA UNII
60V9STC53F
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
ECHA (EC/EINECS)
203-468-6
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
CHEBI
30347
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
EVMPD
SUB13760MIG
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
CAS
107-15-3
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
WIKIPEDIA
ETHYLENEDIAMINE
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
DAILYMED
60V9STC53F
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
NDF-RT
N0000184306
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY Cell-mediated Immunity [PE]
EPA CompTox
DTXSID5021881
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
NCI_THESAURUS
C80898
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
SMS_ID
100000092194
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
HSDB
535
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY
NDF-RT
N0000175629
Created by admin on Mon Mar 31 17:33:06 GMT 2025 , Edited by admin on Mon Mar 31 17:33:06 GMT 2025
PRIMARY Increased Histamine Release [PE]