U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H8N2
Molecular Weight 60.0984
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHYLENEDIAMINE

SMILES

C(CN)N

InChI

InChIKey=PIICEJLVQHRZGT-UHFFFAOYSA-N
InChI=1S/C2H8N2/c3-1-2-4/h1-4H2

HIDE SMILES / InChI
Ethylenediamine is a strongly basic amine useful as a building block in chemical synthesis. It is used as a solvent to dissolve proteins such as albumins, casein and in medicine to stabilize aminophylline when used in injections. Ethylenediamine is used in manufacture of chelating agents (EDTA), epoxy curing agents, dimethylolethylene-urea resins, emulsifying agents, textile lubricants, antifreeze inhibitor. It is also involved in the manufacture of many industrial chemicals and forms derivatives with carboxylic acids, nitriles, alcohols, alkylating agents, carbon disulfide, aldehydes and ketones. It is a basic building block to prepare heterocyclic compound such as imidazolidines.

Approval Year

PubMed

PubMed

TitleDatePubMed
Kinetics and mechanisms of EDTA photocatalytic degradation with TiO2.
2001
Enzymatic, clinical and histologic evaluation of corneal tissues in experimental fungal keratitis in rabbits.
2001 Apr
Salts of 3,5-dinitrobenzoic acid with organic diamines: hydrogen-bonded supramolecular structures in one, two and three dimensions.
2001 Apr
Sustained release of basic fibroblast growth factor and angiogenesis in a novel covalently crosslinked gel of heparin and alginate.
2001 Aug
Synthesis and structure of [K(+)-(2,2)diaza-[18]-crown-6][K3Ge9]-2ethylenediamine: stabilization of the two-dimensional layer (2)(infinity)[K3Ge9(1-)].
2001 Aug 27
Enzymatic properties of sialic acid binding lectin from Rana catesbeiana modified with a water-soluble carbodiimide in the presence of various nucleophiles.
2001 Dec
Cyclodehydration reactions of methyl 9,10-; 10,12-; and 9,1 2-dioxostearates with 1,2-diaminoethane under ultrasonic irradiation.
2001 Feb
NMR paramagnetic relaxation enhancement: test of the controlling influence of zfs rhombicity for S = 1.
2001 Feb
Ancillary ligand effect on the properties of "Mg(thd)2" and crystal structures of [Mg(thd)2(ethylenediamine)]2, [Mg(thd)2(tmeda)], and [Mg(thd)2(trien)].
2001 Feb 12
Inhibition of lignin peroxidase-mediated oxidation activity by ethylenediamine tetraacetic acid and N-N-N'-N'-tetramethylenediamine.
2001 Jan
Phagocytic response of bovine polymorphonuclear leukocytes to different incubation conditions and following exposure to some effectors of phagocytosis and different anticoagulants in vitro.
2001 Jan
Platinum(II) and palladium(II) complexes with dithiocarbamates and amines: synthesis, characterization and cell assay.
2001 Jan 1
Di-tert-butyl phosphate complexes of cobalt(II) and zinc(II) as precursors for ceramic M(PO3)2 and M2P2O7 materials: synthesis, spectral characterization, structural studies, and role of auxiliary ligands.
2001 Jan 29
Potential energy surface crossings and the mechanistic spectrum for intramolecular electron transfer in organic radical cations.
2001 Jan 31
Behaviour of 2-substituted 1,3-indandiones towards aldimines.
2001 Jan-Feb
Comparison of the macromolecular MR contrast agents with ethylenediamine-core versus ammonia-core generation-6 polyamidoamine dendrimer.
2001 Jan-Feb
Preparation of a ribonucleic acid-(polyamidoamine)-(zirconia-urea-formaldehyde resin) high-performance liquid affinity chromatographic stationary phase.
2001 Jul
Tetranuclear mixed-metal M(II)2Cu(II)2 complexes derived from a phenol-based macrocyclic ligand having two N(amine)2O2 and two N(imine)2O2 metal-binding sites.
2001 Jul 16
catena-Poly[dibromozinc(II)-mu-ethylenediamine-N:N']: resolution of structural anomalies resulting from the interpretation of vibrational spectra.
2001 Jun
Biodegradability of ethylenediamine-based complexing agents.
2001 Jun
Development of an ELISA to measure soluble CD163 in biological fluids.
2001 Jun 1
Chromium-51 ethylenediamine tetraacetic acid glomerular filtration rate: a better predictor than glomerular filtration rate calculated by the Cockcroft-Gault formula for renal involvement in systemic lupus erythematosus patients.
2001 Mar
Prognostic importance of the soluble plasminogen activator receptor, suPAR, in plasma from rectal cancer patients.
2001 Mar
Effect of collagenase inhibitors on corneal haze after PRK.
2001 Mar
Rb(4)Hg(5)(Te(2))(2)(Te(3))(2)Te(3), [Zn(en)3](4)In(16)(Te2)4(Te3)Te22, and K2Cu2(Te2)(Te3): novel metal polytellurides with unusual metal-tellurium coordination.
2001 Mar 12
Structures of a tetradentate ferrocenyl ligand and its oxorhenium(V) complex in solution and in the solid state.
2001 Mar 12
Chemoenzymatic synthesis of sucrose-containing aromatic polymers.
2001 Mar 5
[Effect of alpha-lipoic acid preparations on bilirubin and transferrin levels and ferritin iron and transferrin iron content].
2001 Mar-Apr
Sulfite oxidation by iron-grown cells of Thiobacillus ferrooxidans at pH 3 possibly involves free radicals, iron, and cytochrome oxidase.
2001 May
Improving biomaterial properties of collagen films by chemical modification.
2001 May 5
[[Cu(en)(2)](2)Re(4)Te(4)(CN)(12)].5H(2)O and [[Cu(en)(2)](2)Re(6)Te(8)(CN)(6)].5H(2)O: bonding of a transition-metal complex to a rhenium chalcocyanide cluster.
2001 Nov 19
Gold-gold interactions as crystal engineering design elements in heterobimetallic coordination polymers.
2001 Nov 5
The effect of pH and concentration upon aggregation transitions in aqueous solutions of poloxamine T701.
2001 Oct 23
Syntheses, vibrational spectra, and theoretical studies of the adamantanoid Sn(4)Ch(10)(4-) (Ch = Se, Te) anions: X-ray crystal structures of [18-crown-6-K](4)[Sn4Se10]*5en and [18-crown-6-K](4)[Sn4Te10]*3en*2THF.
2001 Sep 10
c-erbB-2 is not a major factor in the development of colorectal cancer.
2002 Feb 12
Nitriles form mixed-coligand complexes with (99m)Tc-HYNIC-peptide.
2002 Jan
Galactosylated alginate as a scaffold for hepatocytes entrapment.
2002 Jan
Syntheses, crystal structures, and density functional theory calculations of the closo-[1-M(CO)(3)(eta(4)-E(9))](4-) (E = Sn, Pb; M = Mo, W) cluster anions and solution NMR spectroscopic characterization of [1-M(CO)(3)(eta(4)-Sn(9))](4-) (M = Cr, Mo, W).
2002 Jan 14
Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum.
2002 Jan 2
Development of preparation methods for and insights obtained from atomic force microscopy of fluid spaces in cortical bone.
2002 Jan-Feb
Three different bonding modes of cyano groups in the coordination polymer [Cu(en)2(H(2)O)][Cu(en)(2)Ni(2)Cu(2)(CN)(10)] x 2H(2)O (en is 1,2-diaminoethane).
2002 Mar
Designed self-assembly of molecular necklaces.
2002 Mar 13
Role of magnesium in nucleotide exchange on the small G protein rac investigated using novel fluorescent Guanine nucleotide analogues.
2002 Mar 19
[Ph(2)Bi-(Ge(9))-BiPh(2)](2-): a deltahedral Zintl ion functionalized by exo-bonded ligands.
2002 Mar 20
Patents
Name Type Language
ETHYLENEDIAMINE
EP   HSDB   II   MART.   MI   USP   WHO-DD  
Systematic Name English
ETHYLENEDIAMINE [MART.]
Common Name English
ETHYLENE DIAMINE
Common Name English
ETHYLENEDIAMINE [HSDB]
Common Name English
ETHYLENEDIAMINE [II]
Common Name English
ETHYLENEDIAMINE [EP MONOGRAPH]
Common Name English
ETHYLENEDIAMINE [INCI]
Common Name English
1,2-DIAMINOETHANE
Systematic Name English
1,2-ETHANEDIAMINE
Systematic Name English
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP]
Common Name English
EDAMINE [INN]
Common Name English
ETHYLENEDIAMINE [USP MONOGRAPH]
Common Name English
EDAMINE
INN  
INN  
Official Name English
ETHYLENEDIAMINE [MI]
Common Name English
ETHYLENEDIAMINE [WHO-DD]
Common Name English
Classification Tree Code System Code
NDF-RT N0000185508
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
EPA PESTICIDE CODE 4205
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
CFR 21 CFR 173.320
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
Code System Code Type Description
RXCUI
4158
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY RxNorm
INN
7141
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
NDF-RT
N0000171131
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY Allergens [Chemical/Ingredient]
MERCK INDEX
M5119
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY Merck Index
DRUG BANK
DB14189
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
ChEMBL
CHEMBL816
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
CONCEPT Industrial Aid
PUBCHEM
3301
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
FDA UNII
60V9STC53F
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
ECHA (EC/EINECS)
203-468-6
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
EVMPD
SUB13760MIG
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
CAS
107-15-3
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
WIKIPEDIA
ETHYLENEDIAMINE
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
NDF-RT
N0000184306
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY Cell-mediated Immunity [PE]
EPA CompTox
107-15-3
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
NCI_THESAURUS
C80898
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
HSDB
535
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY
NDF-RT
N0000175629
Created by admin on Fri Jun 25 20:56:48 UTC 2021 , Edited by admin on Fri Jun 25 20:56:48 UTC 2021
PRIMARY Increased Histamine Release [PE]