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Details

Stereochemistry RACEMIC
Molecular Formula C14H17NO3
Molecular Weight 247.2897
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE

SMILES

CCOC1C=CC2=CC=CC=C2N1C(=O)OCC

InChI

InChIKey=GKQLYSROISKDLL-UHFFFAOYSA-N
InChI=1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Regulation of α₂-adrenoceptor gene expression by chronic lithium treatment in rat brain.
2010-12
Dopamine release induced by atypical antipsychotics in prefrontal cortex requires 5-HT(1A) receptors but not 5-HT(2A) receptors.
2010-11
Extrastriatal dopaminergic circuits of the Basal Ganglia.
2010
Dissociable effects of noradrenaline, dopamine, and serotonin uptake blockade on stop task performance in rats.
2009-08
Action of dexmedetomidine on the substantia gelatinosa neurons of the rat spinal cord.
2008-06
Inhibition of reversed electron transfer and proton transport in the beef heart cytochrome bc1 complex by chemical modification.
2007-03
HPLC Method for Determination of Enantiomeric Purity of a Novel Respiratory Fluoroquinolone: WCK 1152.
2007-02-06
Dequalinium-induced protofibril formation of alpha-synuclein.
2006-02-10
Interactions between adenosine A(2a) and dopamine D2 receptors in the control of [(3)H]GABA release in the globus pallidus of the rat.
2005-09-27
Effect of chronic lithium treatment on the turnover of alpha2-adrenoceptors after chemical inactivation in rats.
2004-12
Effect of alpha 2-adrenoceptor blockade on lithium action in the rat brain.
2003-12-19
Aspartate-186 in the head group of the yeast iron-sulfur protein of the cytochrome bc1 complex contributes to the protein conformation required for efficient electron transfer.
2003-12-08
EMD 281014, a new selective serotonin 5-HT2A receptor antagonist.
2003-07-25
Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2.
2003-03
A yeast mitochondrial ATPase inhibitor interacts with three proteins that are easy to dissociate from the mitochondrial inner membrane.
2002-10
Lead exposure and dorsomedial striatum mediation of fixed interval schedule-controlled behavior.
2002-09
alpha-Synuclein exhibits competitive interaction between calmodulin and synthetic membranes.
2002-09
Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking.
2002-09
Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors.
2002-07
Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [3H]phosphatidylinositols.
2002-03
Dopamine receptors in the subthalamic nucleus are involved in the regulation of muscle tone in the rat.
2002-01-14
Carboxyl residues in the iron-sulfur protein are involved in the proton pumping activity of P. denitrificans bc(1) complex.
2001-12-18
Further characterization of 5-HT1A receptors in the goldfish retina: role of cyclic AMP in the regulation of the in vitro outgrowth of retinal explants.
2001-03
Differential protection and recovery of 5-HT1A receptors from N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) inactivation in regions of rat brain.
2001-02
Self-oligomerization and protein aggregation of alpha-synuclein in the presence of Coomassie Brilliant Blue.
2001-01
The role of the globus pallidus D2 subfamily of dopamine receptors in pallidal immediate early gene expression.
2001
The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.
1994-04
Patents
Name Type Language
2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE
Systematic Name English
EEDQ
MI  
Preferred Name English
1(2H)-QUINOLINECARBOXYLIC ACID, 2-ETHOXY-, ETHYL ESTER
Systematic Name English
BC-681
Code English
EEDQ [MI]
Common Name English
ETHYL 2-ETHOXY-1(2H)-QUINOLINECARBOXYLATE
Systematic Name English
2-ETHOXY-N-(ETHOXYCARBONYL)-1,2-DIHYDROQUINOLINE
Systematic Name English
NSC-147831
Code English
N-CARBETHOXY-2-ETHOXY-1,2-DIHYDROQUINOLINE
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
240-418-2
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
PUBCHEM
27833
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
FDA UNII
60O971AN19
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
EPA CompTox
DTXSID50871969
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
MERCK INDEX
m4836
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY Merck Index
CAS
16357-59-8
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
NSC
147831
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY
WIKIPEDIA
EEDQ
Created by admin on Mon Mar 31 22:42:51 GMT 2025 , Edited by admin on Mon Mar 31 22:42:51 GMT 2025
PRIMARY