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Details

Stereochemistry RACEMIC
Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AMPHECLORAL

SMILES

CC(CC1=CC=CC=C1)\N=C\C(Cl)(Cl)Cl

InChI

InChIKey=VBZDETYCYXPOAK-OVCLIPMQSA-N
InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3/b15-8+

HIDE SMILES / InChI
Amphecloral (INN: amfecloral) is a phenethylamine derivative which was patented in 1960 as an amphetamine pro-drug with prolonged duration of action. Amfecloral was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It is an anorectic drug with little to no stimulant activity. Amphecloral is metabolized to both d-(S)- and l-(R)-amphetamine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Mode of action of psychomotor stimulant drugs.
1970
Chiral toxicology: it's the same thing...only different.
2009 Jul
Patents
Name Type Language
AMPHECLORAL
MI   USAN  
USAN  
Official Name English
AMPHECLORAL [MI]
Common Name English
amfecloral [INN]
Common Name English
AMPHECLORAL [USAN]
Common Name English
BENZENEETHANAMINE, .ALPHA.-METHYL-N-(2,2,2-TRICHLOROETHYLIDENE)-
Systematic Name English
AMFECLORAL
INN  
INN  
Official Name English
α-Methyl-N-(2,2,2-trichloroethylidene)phenethylamine
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C29728
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
NCI_THESAURUS C47795
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
Code System Code Type Description
EVMPD
SUB05414MIG
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
PRIMARY
DRUG CENTRAL
5113
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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NCI_THESAURUS
C90610
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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WIKIPEDIA
Amfecloral
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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EPA CompTox
DTXSID00863571
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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ChEMBL
CHEMBL2105544
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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DRUG BANK
DB08924
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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SMS_ID
100000087215
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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MERCK INDEX
m47
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
PRIMARY Merck Index
CAS
5581-35-1
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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INN
1207
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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FDA UNII
6015XOA0BI
Created by admin on Sat Dec 16 17:29:19 GMT 2023 , Edited by admin on Sat Dec 16 17:29:19 GMT 2023
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