GUANINE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H5N5O
Molecular Weight	151.1261
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(N=CN2)C(=O)N1

InChI

InChIKey=UYTPUPDQBNUYGX-UHFFFAOYSA-N

InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Regulation of gene expression by GC-rich DNA cis-elements.	2001	11237405
Sequence-specific DNA damage induced by UVA radiation in the presence of endogenous and exogenous photosensitizers.	2001	11225203
Ionization mechanism of oligonucleotides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.	2001	11135425
RNA fragmentation studied in a matrix-assisted laser desorption/ionisation tandem quadrupole/orthogonal time-of-flight mass spectrometer.	2001	11135418
NMR interaction studies of aromatic guanyl hydrazones with micelles: model for mechanism of action of cationic antibiotics.	2001	11135187
125I-Antisauvagine-30: a novel and specific high-affinity radioligand for the characterization of corticotropin-releasing factor type 2 receptors.	2001	11077077
Base sequence-specific attack of stilbene estrogen metabolite(s) on the mitochondrial DNA: implications in the induction of instability in the mitochondrial genome in the kidney of Syrian hamsters.	2001 Apr	11254879
Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer.	2001 Feb	11239755
Quantification and validation of enzyme immunoassay for urinary aflatoxin B1-N7-guanine adduct for biological monitoring of aflatoxins.	2001 Feb	11235100
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis.	2001 Feb	11181815
Structure of an RNA duplex with an unusual G.C pair in wobble-like conformation at 1.6 A resolution.	2001 Feb	11173467
De novo mutation in the mitochondrial tRNALeu(UUR) gene (A3243G) with rapid segregation resulting in MELAS in the offspring.	2001 Feb	11168879
Characterization of the mouse liver fructose-1,6-bisphosphatase gene.	2001 Feb 21	11250076
Cloning and direct G-protein regulation of phospholipase D from tobacco.	2001 Feb 26	11239820
Kinetic and mechanistic properties of biotin sulfoxide reductase.	2001 Feb 6	11170471
Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.	2001 Feb 6	11170441
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis.	2001 Feb 9	11110788
Quantum chemistry predicted correlations between geometric isomerism (conformation) of -OH and =NH substituents and typical group frequencies of nucleic acid bases: cytosine.	2001 Jan	11209867
Antibody recognition of melphalan adducts characterized using immobilized DNA: enhanced alkylation of G-Rich regions in cells compared to in vitro.	2001 Jan	11170510
Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion.	2001 Jan	11134924
Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry.	2001 Jan 1	11196182
Regions of low single-nucleotide polymorphism incidence in human and orangutan xq: deserts and recent coalescences.	2001 Jan 1	11161800
Genetic study of SOX9 in a case of campomelic dysplasia.	2001 Jan 15	11223854
The N-terminal domain of the Caulobacter crescentus CgtA protein does not function as a guanine nucleotide exchange factor.	2001 Jan 26	11231024
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites.	2001 Jan 26	11062246
The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus.	2001 Jan 5	11146053
A seminested PCR test for simultaneous detection of two common mutations (35delG and 167delT) in the connexin-26 gene.	2001 Mar	11257213
Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid.	2001 Mar	11255442
New biochemical markers in Alzheimer disease.	2001 Mar	11255437
Substrate assisted catalysis -- application to G proteins.	2001 Mar	11246021
Metabolism of the beta-oxidized intermediates of N-nitrosodi-n-propylamine: N-nitroso-beta-hydroxypropylpropylamine and N-nitroso-beta-oxopropylpropylamine.	2001 Mar	11238192
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke.	2001 Mar	11238174
Inactivation of human O(6)-alkylguanine-DNA alkyltransferase by modified oligodeoxyribonucleotides containing O(6)-benzylguanine.	2001 Mar	11181929
Conjugative metabolism of 1,2-dibromoethane in mitochondria: disruption of oxidative phosphorylation and alkylation of mitochondrial DNA.	2001 Mar 1	11239503
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction.	2001 Mar 15	11250907
A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC).	2001 Mar 23	11254379
Evaluation of the mutagenic potential of the principal DNA adduct of acrolein.	2001 Mar 23	11106660
Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit.	2001 Mar 7	11255023

Patents

Name

Type

Language

GUANINE

Official Name

English

GUANINE [EP IMPURITY]

Common Name

English

CI 75170

Official Name

English

2-AMINOHYPOXANTHINE

Common Name

English

2-AMINO-1,7-DIHYDRO-6H-PURIN-6-ONE [WHO-IP]

Systematic Name

English

GUANINE [INCI]

Common Name

English

GANCICLOVIR IMPURITY F [EP IMPURITY]

Common Name

English

C.I. NO. 75170 (GUANINE)

Common Name

English

6H-PURIN-6-ONE, 2-AMINO-1,7-DIHYDRO-

Systematic Name

English

VALGANCICLOVIR HYDROCHLORIDE IMPURITY B [USP IMPURITY]

Common Name

English

GUANINE [USP IMPURITY]

Common Name

English

VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY A [EP IMPURITY]

Common Name

English

ACICLOVIR IMPURITY B [EP IMPURITY]

Common Name

English

GUANINE [WHO-IP]

Common Name

English

GUANINE [USP-RS]

Common Name

English

CI 75170 [INCI]

Common Name

English

GUANINE [HSDB]

Common Name

English

ACICLOVIR IMPURITY B [WHO-IP]

Common Name

English

GUANINE [MI]

Common Name

English

VALACICLOVIR HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

LOINC

78695-4