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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ASPARAGINE

SMILES

N[C@@H](CC(N)=O)C(O)=O

InChI

InChIKey=DCXYFEDJOCDNAF-REOHCLBHSA-N
InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1

HIDE SMILES / InChI

Description

Asparagine is a non-essential amino acid, which is synthesized in the human body from L-aspartate by Asparagine synthetase. Asparagine is required for the synthesis of many important cellular proteins in normal human cells. Many tumor cells do not have this capacity, due to a lack of the enzyme L-asparagine synthetase, and therefore require an exogenous supply of the amino acid. This amino acid participates in the functions of the brain and nervous system. Asparagine may come from food or be taken as a dietary supplement.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
500 mg or 1 capsule daily as a dietary supplement or as recommended by a healthcare practitioner.
Route of Administration: Oral
In Vitro Use Guide
HeLa cells were treated with 0.1 mM asparagine and at this concentration, the amino acid promoted cancer cell proliferation in 3 times.