Details
| Stereochemistry | EPIMERIC |
| Molecular Formula | C25H36N2O8 |
| Molecular Weight | 492.5619 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC(O)=C(O)C=C1C(=O)OC[C@H](CNC(C)(C)CNC(=O)C2CCOC2)OC(=O)C3(C)CC3
InChI
InChIKey=ANXXSWNMHQHOQC-DJNXLDHESA-N
InChI=1S/C25H36N2O8/c1-15-9-19(28)20(29)10-18(15)22(31)34-13-17(35-23(32)25(4)6-7-25)11-27-24(2,3)14-26-21(30)16-5-8-33-12-16/h9-10,16-17,27-29H,5-8,11-14H2,1-4H3,(H,26,30)/t16?,17-/m0/s1
Othera Pharmaceuticals originally developed OT-730 (now known as QLT 091568) as an oculoselective beta-blocker for reducing the elevated intraocular pressure associated with glaucoma. OT-730 was involved in phase II clinical trial in patients with ocular hypertension or open-angle glaucoma. However, these studies were discontinued. At December 30, 2009, QLT Inc. acquired OT-730.
Originator
Approval Year
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Preferred Name | English | ||
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5WVS67PLAL
Created by
admin on Tue Apr 01 16:30:39 GMT 2025 , Edited by admin on Tue Apr 01 16:30:39 GMT 2025
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OT-730
Created by
admin on Tue Apr 01 16:30:39 GMT 2025 , Edited by admin on Tue Apr 01 16:30:39 GMT 2025
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PRIMARY | The purpose of this study is to evaluate the safety and potential efficacy of a new drug, OT-730 ophthalmic solution (eye drops), in reducing intraocular pressure in the eyes of patients with open angle glaucoma or ocular hypertension. It will be compared with commercial timolol and placebo eye drops. | ||
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870809-51-1
Created by
admin on Tue Apr 01 16:30:39 GMT 2025 , Edited by admin on Tue Apr 01 16:30:39 GMT 2025
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11554979
Created by
admin on Tue Apr 01 16:30:39 GMT 2025 , Edited by admin on Tue Apr 01 16:30:39 GMT 2025
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PRIMARY |
ACTIVE MOIETY
