Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H25N3O2 |
| Molecular Weight | 351.4421 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC(=O)C1=CC=C(OC2=CC=C3CCN(CCC3=C2)C4CCC4)N=C1
InChI
InChIKey=WROHEWWOCPRMIA-UHFFFAOYSA-N
InChI=1S/C21H25N3O2/c1-22-21(25)17-6-8-20(23-14-17)26-19-7-5-15-9-11-24(18-3-2-4-18)12-10-16(15)13-19/h5-8,13-14,18H,2-4,9-12H2,1H3,(H,22,25)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain. | 2008 Aug 15 |
|
| 11C-GSK189254: a selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by PET. | 2009 Dec |
|
| Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice. | 2009 May |
|
| Regional differential effects of the novel histamine H3 receptor antagonist 6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on histamine release in the central nervous system of freely moving rats. | 2010 Jan |
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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300000042429
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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5T4TX6CO53
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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9798547
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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720690-73-3
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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GSK-189254
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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DTXSID801005982
Created by
admin on Sat Dec 16 07:01:28 GMT 2023 , Edited by admin on Sat Dec 16 07:01:28 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
