PHYTOCHLORIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C34H36N4O6
Molecular Weight	596.6728
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1=C(C)C2=NC1=CC3=C(C)C(C(O)=O)=C(N3)C(CC(O)=O)=C4N=C(C=C5NC(=C2)C(C=C)=C5C)[C@@H](C)[C@@H]4CCC(O)=O

InChI

InChIKey=VAJLRIOJDADNAT-HHGNVTQFSA-N

InChI=1S/C34H36N4O6/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23/h7,12-14,17,21,35,38H,1,8-11H2,2-6H3,(H,39,40)(H,41,42)(H,43,44)/b23-12-,24-13-,25-12-,26-14-,27-13-,28-14-,32-22-,33-22-/t17-,21-/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
platelet aggregation 76 Target ID: GO:0070527 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23997795 \| https://www.ncbi.nlm.nih.gov/pubmed/1860495	Inhibitor 8297

PubMed

Title	Date	PubMed
Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp120 envelope glycoprotein of the human immunodeficiency virus type 1.	1994 Apr 15	8164251
A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody.	1999 Jun	10403680
[Targeting of chlorine E6 by EGF increasing its photodynamic activity in selective ways].	2000	11004908
Interaction of porphyrins with human organic anion transporting polypeptide 1B1.	2009 Nov 10	19560444
Hollow MnO(2) as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses.	2017 Oct 12	29026068
G-Quadruplex-Based Nanoscale Coordination Polymers to Modulate Tumor Hypoxia and Achieve Nuclear-Targeted Drug Delivery for Enhanced Photodynamic Therapy.	2018 Nov 14	30303384

Patents

Name

Type

Language

PHYTOCHLORIN

Common Name

English

PHOTOLON

Common Name

English

2-PORPHINEPROPIONIC ACID, 18-CARBOXY-20-(CARBOXYMETHYL)-13-ETHYL-2.BETA.,3-DIHYDRO-3.BETA.,7,12,17-TETRAMETHYL-8-VINYL-

Common Name

English

CHLORIN A6

Common Name

English

PHOTOCHLORINE

Common Name

English

CHLORINE E6

Common Name

English

21H,23H-PORPHINE-2-PROPANOIC ACID, 18-CARBOXY-20-(CARBOXYMETHYL)-8-ETHENYL-13-ETHYL-2,3-DIHYDRO-3,7,12,17-TETRAMETHYL-, (2S-TRANS)-

Common Name

English

CHLORIN E6

Common Name

English

21H,23H-PORPHINE-7-PROPANOIC ACID, 3-CARBOXY-5-(CARBOXYMETHYL)-13-ETHENYL-18-ETHYL-7,8-DIHYDRO-2,8,12,17-TETRAMETHYL-, (7S,8S)-

Common Name

English

PHYTOCHLORIN E6

Common Name

English

Phytochlorin [WHO-DD]

Common Name

English

PHYTOCHLORIN [MI]

Common Name

English

PHYTOCHLORINE E6

Common Name

English

CHLORINE A6

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

243-209-4