U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Cl.Sr
Molecular Weight 159.813
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STRONTIUM CHLORIDE SR-89

SMILES

[Cl-].[Cl-].[89Sr++]

InChI

InChIKey=AHBGXTDRMVNFER-FCHARDOESA-L
InChI=1S/2ClH.Sr/h2*1H;/q;;+2/p-2/i;;1+1

HIDE SMILES / InChI
Strontium SR-89 is a radioactive isotope of strontium. Strontium-89 decays by beta emission with a half-life of 50.5 days. Beta-particles produced by radioactive decay penetrate tissues at a range of approximately 8 mm. Strontium SR-89 is used in medicine for the relief of bone pain in patients with painful skeletal metastases. Following intravenous injection, soluble strontium compounds behave like their calcium analogs, clearing rapidly from the blood and selectively localizing in bone mineral. Uptake of strontium by bone occurs preferentially in sites of active osteogenesis; thus primary bone tumors and areas of metastatic involvement (blastic lesions) can accumulate significantly greater concentrations of strontium than surrounding normal bone.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Metastron

Approved Use

Metastron (Strontium-89 Chloride Injection) is indicated for the relief of bone pain in patients with painful skeletal metastases. The presence of bone metastases should be confirmed prior to therapy.

Launch Date

1993
Name Type Language
STRONTIUM CHLORIDE SR-89
ORANGE BOOK  
Common Name English
STRONTIUM CHLORIDE SR 89 [USP IMPURITY]
Common Name English
STRONTIUM CHLORIDE, SR-89
Common Name English
STRONTIUM CHLORIDE SR 89
MI   USAN   USP  
USAN  
Official Name English
METASTRON
Brand Name English
STRONTIUM 89 CHLORIDE
Common Name English
STRONTIUM CHLORIDE SR-89 [ORANGE BOOK]
Common Name English
STRONTIUM-89 CHLORIDE [VANDF]
Common Name English
STRONTIUM (89SR) CHLORIDE [JAN]
Common Name English
STRONTIUM CHLORIDE SR 89 [MI]
Common Name English
Strontium (89 sr) chloride [WHO-DD]
Common Name English
STRONTIUM CHLORIDE SR 89 [USAN]
Common Name English
STRONTIUM (89SR) CHLORIDE
JAN  
Common Name English
STRONTIUM-89 CHLORIDE
VANDF  
Common Name English
SMS-2PA
Code English
SMS2PA
Code English
Classification Tree Code System Code
NDF-RT N0000175872
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
WHO-VATC QV10BX01
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
NCI_THESAURUS C1446
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
WHO-ATC V10BX01
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
Code System Code Type Description
SMS_ID
100000090517
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PRIMARY
EVMPD
SUB12334MIG
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PRIMARY
USAN
GG-12
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PRIMARY
RXCUI
281890
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PRIMARY RxNorm
DRUG BANK
DB09498
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PRIMARY
FDA UNII
5R78837D4A
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PRIMARY
EPA CompTox
DTXSID10191655
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MERCK INDEX
m10240
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PRIMARY Merck Index
DAILYMED
5R78837D4A
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
PRIMARY
LACTMED
Strontium Chloride Sr 89
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
PRIMARY
EVMPD
SUB127189
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ALTERNATIVE
MESH
C025700
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PRIMARY
CAS
38270-90-5
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PRIMARY
PUBCHEM
71435
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PRIMARY
CHEMBL
CHEMBL2219640
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
PRIMARY
NCI_THESAURUS
C1238
Created by admin on Fri Dec 15 15:44:39 GMT 2023 , Edited by admin on Fri Dec 15 15:44:39 GMT 2023
PRIMARY