Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H22N4O4 |
Molecular Weight | 334.3703 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COCCOC1=C(OC)C=C(CC2=C(N)N=C(N)N=C2)C=C1OC
InChI
InChIKey=WSWJIZXMAUYHOE-UHFFFAOYSA-N
InChI=1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20)
CNS Activity
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P0ABQ4 Gene ID: 944790.0 Gene Symbol: folA Target Organism: Escherichia coli (strain K12) Sources: https://www.ncbi.nlm.nih.gov/pubmed/43863 |
3.2 nM [Ki] |
PubMed
Title | Date | PubMed |
---|---|---|
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii. | 1995 Nov 24 |
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Order-disorder enantiotropy, monotropy, and isostructurality in a tetroxoprim-sulfametrole 1:1 molecular complex: Crystallographic and thermal studies. | 2003 Nov |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C2153
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WHO-ATC |
J01EE06
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65450
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TETROXOPRIM
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3814
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CHEMBL32039
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C76644
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53808-87-0
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258-789-4
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C023507
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DTXSID80202085
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SUB10953MIG
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100000082722
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37999
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2615
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m10668
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5R6712AY0K
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ACTIVE MOIETY