Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H12N3O4P |
| Molecular Weight | 197.1295 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(CCOP(O)(O)=O)C(N)=N
InChI
InChIKey=FOIPWTMKYXWFGC-UHFFFAOYSA-N
InChI=1S/C4H12N3O4P/c1-7(4(5)6)2-3-11-12(8,9)10/h2-3H2,1H3,(H3,5,6)(H2,8,9,10)
Creatinolfosfate (or creatinol-O-phosphate, or COP) possesses anti-ischemic and anti-arrhythmic activities associated with improved ionic balance and heart performance. This compound exerts its cardioprotective effect by action on anaerobic glycolysis. The results of the toxicological studies showed that creatinolfosfate didn’t have side effects.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Treatment of antihiasthenic syndromes (with creatinol-O-phosphate)]. | 1976 Sep 30 |
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| Protective effect of creatinol O-phosphate (COP) on ventricular fibrillation and death induced by intravenous CaCl2 in mice. | 1979 |
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| An analysis of the reduction by creatinol O-phosphate of the myocardial lesions evoked by isoprenaline in the rat. | 1979 |
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| Creatinol O-phosphate therapy in patients with inadequate coronary circulation. Double-blind clinical trial. | 1979 |
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| Effects of creatinol O-phosphate on serum enzymes in acute myocardial infarction. | 1979 |
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DSLD |
676 (Number of products:58)
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WHO-ATC |
C01EB05
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WHO-VATC |
QC01EB05
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C77832
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100000083736
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5O564RN1QD
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CHEMBL2104114
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C1505
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CONCEPT | Dietary Supplement | ||
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CREATINOLFOSFATE
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DTXSID50219100
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DB13071
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23342
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SUB06817MIG
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2460
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230-011-8
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6903-79-3
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739
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PRIMARY |
ACTIVE MOIETY
