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Details

Stereochemistry ACHIRAL
Molecular Formula C16H12O5
Molecular Weight 284.2635
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GENKWANIN

SMILES

COC1=CC2=C(C(=O)C=C(O2)C3=CC=C(O)C=C3)C(O)=C1

InChI

InChIKey=JPMYFOBNRRGFNO-UHFFFAOYSA-N
InChI=1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
The roles of a flavone-6-hydroxylase and 7-O-demethylation in the flavone biosynthetic network of sweet basil.
2013-01-18
Antibacterial and antimycobacterial lignans and flavonoids from Larrea tridentata.
2012-12
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.
2011-05-01
Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.
2010-12-13
Soybean metabolites regulated in root hairs in response to the symbiotic bacterium Bradyrhizobium japonicum.
2010-08
Introduction of distillate rosemary leaves into the diet of the Murciano-Granadina goat: transfer of polyphenolic compounds to goats' milk and the plasma of suckling goat kids.
2010-07-28
Evaluation of estrogen receptor Beta binding of pruni cortex and its constituents.
2010-07
A simple and efficient protocol for large-scale preparation of three flavonoids from the flower of Daphne genkwa by combination of macroporous resin and counter-current chromatography.
2010-07
Flavonoids from the aerial parts of Diplomorpha canescens.
2010-06
Flavonoids and phenolic compounds from Rosmarinus officinalis.
2010-05-12
Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells.
2010-05
Blechnum orientale Linn - a fern with potential as antioxidant, anticancer and antibacterial agent.
2010-04-30
Two new coumarins from the chloroform extract of Angelica urumiensis from Iran.
2010-04
[Chemical constituents from flowers of Chrysanthemum indicum].
2010-03
Relationship between the antioxidant capacity and effect of rosemary (Rosmarinus officinalis L.) polyphenols on membrane phospholipid order.
2010-01-13
[Studies on the chemical constituents from Daphne tangutica].
2009-12
CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.
2009-10-29
Sesquiterpenoids from Teucrium ramosissimum.
2009-07-17
[Chemical constituents and antitumor activity on leukemia K562 cell of Leonurus heterophyllus].
2009-07
Quantitative determination of flavonoids by column high-performance liquid chromatography with mass spectrometry and ultraviolet absorption detection in Artemisia afra and comparative studies with various species of Artemisia plants.
2009-06-03
Biological synthesis of 7-O-methyl Apigenin from naringenin using escherichia coli expressing two genes.
2009-05
[Studies on chemical constituents of Daphne genkwa].
2009-04
[Studies on chemical constituents of leaves of Aquilaria sinensis].
2009-04
Flavonoids and cinnamic acid derivatives as inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
2009-03-25
Sakuranetin induces adipogenesis of 3T3-L1 cells through enhanced expression of PPARgamma2.
2008-08-08
[Chemical constituents from herb of Gueldenstaedtia stenophylla].
2008-07
[Studies on chemical constituents from herbs of Taraxacum mongolicum].
2008-05
Laxative effect of agarwood leaves and its mechanism.
2008-02
Flavonoids from Daphne giraldii Nitsche.
2008
Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida.
2007-03
Prostaglandin inhibitory and antioxidant components of Cistus laurifolius, a Turkish medicinal plant.
2006-12-06
Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes.
2006-09-15
[Studies on chemical constituents in spikes of Schizonepeta tenuifolia].
2006-08
Isolation of flavonoids, a biscoumarin and an amide from the flower buds of Daphne genkwa and the evaluation of their anti-complement activity.
2006-07
Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli.
2006-03
[A new dicoumarin from stem bark of Wikstroemia indica].
2006-01
[Study on chemical constituents of Lagotis yunnanensis].
2005-09
[Studies on flavonoids from herb of Artemisia ordosica].
2005-09
[Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation].
2005-09
[Studies on the chemical constituents in roots of Daphne odora var. atrocaulis].
2005-04
Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. postulation of a biosynthetic pathway.
2004-08-11
Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae).
2004-08
Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.
2004-06
Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity.
2004-01
Determination of phenolic antioxidant compounds produced by calli and cell suspensions of sage (Salvia officinalis L.).
2003-09
Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity.
2003-07-16
In vitro antiplasmodial evaluation of medicinal plants from Zimbabwe.
2003-02
Subcritical water extraction of antioxidant compounds from rosemary plants.
2003-01-15
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.
1994-08-03
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
1991-01-01
Patents
Name Type Language
GENKWANIN
Common Name English
7-METHOXYAPIGENIN
Preferred Name English
4',5-DIHYDROXY-7-METHOXYFLAVONE
Systematic Name English
Code System Code Type Description
FDA UNII
5K3I5D6B2B
Created by admin on Mon Mar 31 19:22:14 GMT 2025 , Edited by admin on Mon Mar 31 19:22:14 GMT 2025
PRIMARY
WIKIPEDIA
GENKWANIN
Created by admin on Mon Mar 31 19:22:14 GMT 2025 , Edited by admin on Mon Mar 31 19:22:14 GMT 2025
PRIMARY
EPA CompTox
DTXSID80195908
Created by admin on Mon Mar 31 19:22:14 GMT 2025 , Edited by admin on Mon Mar 31 19:22:14 GMT 2025
PRIMARY
PUBCHEM
5281617
Created by admin on Mon Mar 31 19:22:14 GMT 2025 , Edited by admin on Mon Mar 31 19:22:14 GMT 2025
PRIMARY
CAS
437-64-9
Created by admin on Mon Mar 31 19:22:14 GMT 2025 , Edited by admin on Mon Mar 31 19:22:14 GMT 2025
PRIMARY