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Details

Stereochemistry ACHIRAL
Molecular Formula C8H9NO4
Molecular Weight 183.1614
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-PYRIDOXIC ACID

SMILES

CC1=NC=C(CO)C(C(O)=O)=C1O

InChI

InChIKey=HXACOUQIXZGNBF-UHFFFAOYSA-N
InChI=1S/C8H9NO4/c1-4-7(11)6(8(12)13)5(3-10)2-9-4/h2,10-11H,3H2,1H3,(H,12,13)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of folic acid supplementation to rations differing in the concentrate to roughage ratio on ruminal fermentation, nutrient flow at the duodenum, and on serum and milk variables of dairy cows.
2010-12
Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk.
2010-10
Biochemical risk indices, including plasma homocysteine, that prospectively predict mortality in older British people: the National Diet and Nutrition Survey of People Aged 65 Years and Over.
2010-09
Topology of 4-Pyridoxic acid dehydrogenase in transformed Escherichia coli cells.
2010-02
Enhancement of calcium/vitamin d supplement efficacy by administering concomitantly three key nutrients essential to bone collagen matrix for the treatment of osteopenia in middle-aged women: a one-year follow-up.
2010-01
Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition.
2010-01
Development of simultaneous enzymatic assay method for all six individual vitamin B6 forms and pyridoxine-beta-glucoside.
2010
Effect of fasting on the urinary excretion of water-soluble vitamins in humans and rats.
2010
Vitamin B6 metabolism in chronic kidney disease--relation to transsulfuration, advanced glycation and cardiovascular disease.
2010
Photophysics and photochemical studies of the vitamin B6 group and related derivatives.
2009-11-26
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate.
2009-11
Application of the high-performance liquid chromatography method with coulometric detection for determination of vitamin B(6) in human plasma and serum.
2009-10-01
Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
2009-08-13
Effects of 21 days of bed rest, with or without artificial gravity, on nutritional status of humans.
2009-07
A simplified protein precipitation and filtration procedure for determining serum vitamin B6 by high-performance liquid chromatography.
2009-05-01
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry.
2009-05
Gene identification and characterization of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase.
2009-04
Study Protocol: randomised controlled trial to investigate the functional significance of marginal riboflavin status in young women in the UK (RIBOFEM).
2009-03-26
Comparison of the nicotinamide catabolism among rat strains.
2009-02
Effect of selenium status and supplementation with high-selenium yeast on plasma homocysteine and B vitamin concentrations in the UK elderly.
2008-11
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
2008-10
Gene identification and characterization of the pyridoxine degradative enzyme 4-pyridoxic acid dehydrogenase from the nitrogen-fixing symbiotic bacterium Mesorhizobium loti MAFF303099.
2008-05
Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen.
2008-04
Inhibitory and structural studies of novel coenzyme-substrate analogs of human histidine decarboxylase.
2008-03
Determination of individual vitamin B(6) compounds based on enzymatic conversion to 4-pyridoxolactone.
2008-02
Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid.
2008
PLP catabolism: identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099.
2007-12
Simultaneous fluorometric resolution of pyridoxal, pyridoxamine and 4-pyridoxic acid using chemometric methods.
2007-04
Vitamin B6 status assessment in relation to dietary intake in high school students aged 16-18 years.
2007-04
Chelation of UO(2)(2+) by vitamin B6 complex derivatives: synthesis and characterization of [UO2(beta-pyracinide)2(H2O)] and [UO2(Pyr2en)DMSO]Cl2{Pyr2en=N,N'-ethylenebis(pyridoxylideneiminato)}. A useful modeling of assimilation of uranium by living beings.
2006-10
Vitamin B6 supplementation increases immune responses in critically ill patients.
2006-10
B-vitamin status and concentrations of homocysteine in Austrian omnivores, vegetarians and vegans.
2006
Effects of excess pantothenic acid administration on the other water-soluble vitamin metabolisms in rats.
2005-12
Pyridoxal phosphate inhibits the group I intron splicing.
2005-12
Use of chlorite to improve HPLC detection of pyridoxal 5'-phosphate.
2005-09-05
Inhibition of glycosylation processes: the reaction between pyridoxamine and glucose.
2005-07
Multianalyte quantification of vitamin B6 and B2 species in the nanomolar range in human plasma by liquid chromatography-tandem mass spectrometry.
2005-07
Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis.
2005
Inflammation causes tissue-specific depletion of vitamin B6.
2005
Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.
2005
Clinical analysis of vitamin B(6): determination of pyridoxal 5'-phosphate and 4-pyridoxic acid in human serum by reversed-phase high-performance liquid chromatography with chlorite postcolumn derivatization.
2004-10-15
B-6 vitamers and 4-pyridoxic acid in the plasma, erythrocytes, and urine of postmenopausal women.
2004-10
Major factors modulating the serum oxalic acid level in hemodialysis patients.
2004-09-01
Plasma pyridoxal 5'-phosphate is a significant indicator of immune responses in the mechanically ventilated critically ill.
2004-06-20
Vitamin B6 metabolites in idiopathic calcium stone formers: no evidence for a link to hyperoxaluria.
2004-02
Plasma taurine and cysteine levels following an oral methionine load: relationship with coronary heart disease.
2004-01
Optimisation and validation of a sensitive high-performance liquid chromatography assay for routine measurement of pyridoxal 5-phosphate in human plasma and red cells using pre-column semicarbazide derivatisation.
2003-07-25
[Connection between changing the vitamin and immune status and the character of the throat microflora in patients with chronic tonsillitis].
2003
[The effect of riboflavin supply on metabolism of water-soluble vitamins].
1993-09-01
Plasma B-6 vitamer and plasma and urinary 4-pyridoxic acid concentrations in young women as determined using high performance liquid chromatography.
1991-09
Patents

Patents

Name Type Language
4-PYRIDOXIC ACID
MI  
Common Name English
NSC-41814
Preferred Name English
4-PYRIDOXIC ACID [MI]
Common Name English
PYRIDOXIC ACID, 4-
Common Name English
Code System Code Type Description
CHEBI
17405
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
CAS
82-82-6
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-440-8
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
PUBCHEM
6723
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
FDA UNII
5K18793O8D
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
NSC
41814
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY
MERCK INDEX
m9364
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID20861650
Created by admin on Mon Mar 31 19:34:09 GMT 2025 , Edited by admin on Mon Mar 31 19:34:09 GMT 2025
PRIMARY