Details
Stereochemistry | RACEMIC |
Molecular Formula | C18H22ClNO.ClH |
Molecular Weight | 340.287 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(C)CCOC(C)(C1=CC=CC=C1)C2=CC=C(Cl)C=C2
InChI
InChIKey=PAQUKACYLLABHB-UHFFFAOYSA-N
InChI=1S/C18H22ClNO.ClH/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16;/h4-12H,13-14H2,1-3H3;1H
DescriptionCurator's Comment: Description was created based on several sources, including
https://www.drugs.com/international/systral.html
http://en.pharmacodia.com/web/drug/1_10746.html
Curator's Comment: Description was created based on several sources, including
https://www.drugs.com/international/systral.html
http://en.pharmacodia.com/web/drug/1_10746.html
Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and was formerly used in the sympathomimetic treatment of parkinsonism. Histamine receptor H1 antagonist. Chlorphenoxamine is used to treat Allergic conditions, it is reported as an ingredient of Systral in Germany, Malta, Portugal, Thailand, Turkey.
CNS Activity
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
[Antimycobacterial antihistaminics]. | 1989 Aug |
|
Simultaneous determination of caffeine, 8-chlorotheophylline, and chlorphenoxamine hydrochloride in ternary mixtures by ratio-spectra zero-crossing first-derivative spectrophotometric and chemometric methods. | 2005 Jul-Aug |
Patents
Sample Use Guides
Topical/Cutaneous
Allergic conditions
Adult: Apply when required several times daily.
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20003827
Unknown
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29578
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NCI_THESAURUS |
C29704
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11223
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m3457
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SUB01250MIG
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100000084719
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CHEMBL2110774
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DTXSID80971587
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DBSALT002453
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C76671
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C100100
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235422
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209-227-1
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562-09-4
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5I159322PY
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ACTIVE MOIETY
SUBSTANCE RECORD