Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C15H21IN2O3 |
Molecular Weight | 400.2444 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN1CCC[C@H]1CNC(=O)C2=C(O)C([123I])=CC=C2OC
InChI
InChIKey=CANPFCFJURGKAX-SCBSARHOSA-N
InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1/i16-4
IOLOPRIDE I-123 (also known as I-123 iodobenzamide), a radioactive drug that can be seen by Single-photon emission computed tomography. This drug binds to the some dopamine receptors and can be used in the neonatal period. It shows the biochemical maturation of D2 receptors and also manifests the deleterious effect of perinatal hypoxic-ischemic events on D2 receptors.
Approval Year
PubMed
Title | Date | PubMed |
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Imaging of D2 dopamine receptors of patients with Parkinson's disease using single photon emission computed tomography and iodobenzamide I 123. | 1993 May |
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Iodine-123-iodobenzamide binding in parkinsonism: reduction by dopamine agonists but not L-Dopa. | 1996 Jul |
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D2 receptor imaging in neonates using I-123 iodobenzamide brain SPECT. | 2001 Jan |
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Classification Tree | Code System | Code | ||
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WHO-ATC |
V09AB02
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WHO-VATC |
QV09AB02
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NCI_THESAURUS |
C2124
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admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
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11133125
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113716-48-6
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100000083658
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C90939
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DTXSID50150544
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5E76SOQ99K
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7356
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SUB08231MIG
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CHEMBL8475
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IODOBENZAMIDE
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ACTIVE MOIETY