U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C15H21IN2O3
Molecular Weight 400.2444
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IOLOPRIDE I-123

SMILES

CCN1CCC[C@H]1CNC(=O)C2=C(O)C([123I])=CC=C2OC

InChI

InChIKey=CANPFCFJURGKAX-SCBSARHOSA-N
InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1/i16-4

HIDE SMILES / InChI
IOLOPRIDE I-123 (also known as I-123 iodobenzamide), a radioactive drug that can be seen by Single-photon emission computed tomography. This drug binds to the some dopamine receptors and can be used in the neonatal period. It shows the biochemical maturation of D2 receptors and also manifests the deleterious effect of perinatal hypoxic-ischemic events on D2 receptors.

Approval Year

PubMed

PubMed

TitleDatePubMed
Imaging of D2 dopamine receptors of patients with Parkinson's disease using single photon emission computed tomography and iodobenzamide I 123.
1993 May
Iodine-123-iodobenzamide binding in parkinsonism: reduction by dopamine agonists but not L-Dopa.
1996 Jul
D2 receptor imaging in neonates using I-123 iodobenzamide brain SPECT.
2001 Jan
Name Type Language
IOLOPRIDE I-123
Common Name English
BENZAMIDE, N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(IODO-123I)-6-METHOXY-
Systematic Name English
IOLOPRIDE I 123
Common Name English
S-(-)-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(123I)IODO-6-METHOXYBENZAMIDE
Common Name English
IBZM I-123
Common Name English
(I123)IBZM
Common Name English
123I-IBZM
Common Name English
BENZAMIDE, N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(IODO-123I)-6-METHOXY-, (S)-
Common Name English
Iolopride (123 i) [WHO-DD]
Common Name English
iolopride (¹²³I) [INN]
Common Name English
IOLOPRIDE ((SUP 123)I)
Common Name English
IOLOPRIDE (123 I)
WHO-DD  
Common Name English
N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-6-HYDROXY-5-(((SUP 123)I)IODO)-O-ANISAMIDE
Common Name English
IODOBENZAMIDE I-123
Common Name English
IOLOPRIDE (123I)
INN  
INN  
Official Name English
IOLOPRIDE, I-123
Common Name English
Classification Tree Code System Code
WHO-ATC V09AB02
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
WHO-VATC QV09AB02
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
Code System Code Type Description
PUBCHEM
11133125
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
CAS
113716-48-6
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
SMS_ID
100000083658
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
NCI_THESAURUS
C90939
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID50150544
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
FDA UNII
5E76SOQ99K
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
INN
7356
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
EVMPD
SUB08231MIG
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
ChEMBL
CHEMBL8475
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY
WIKIPEDIA
IODOBENZAMIDE
Created by admin on Fri Dec 15 17:26:40 GMT 2023 , Edited by admin on Fri Dec 15 17:26:40 GMT 2023
PRIMARY