MERCAPTOMERIN

US Previously Marketed

First approved in 1949

Details

Stereochemistry	MIXED
Molecular Formula	C16H27HgNO6S
Molecular Weight	562.04
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC(CNC(=O)C1CCC(C)(C(O)=O)C1(C)C)C[Hg]SCC(O)=O

InChI

InChIKey=JGMQLDDGSMLGDU-UHFFFAOYSA-M

InChI=1S/C14H24NO4.C2H4O2S.Hg/c1-9(19-5)8-15-11(16)10-6-7-14(4,12(17)18)13(10,2)3;3-2(4)1-5;/h9-10H,1,6-8H2,2-5H3,(H,15,16)(H,17,18);5H,1H2,(H,3,4);/q;;+1/p-1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18137278 | https://www.ncbi.nlm.nih.gov/pubmed/18123664 | https://www.ncbi.nlm.nih.gov/pubmed/13182225

MERCAPTOMERIN is a mercurial diuretic used for the treatment of congestive heart failure. It is an effective diuretic not only when given intramuscularly and intravenously but also when given subcutaneously.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Congestive Heart Failure 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18137278 http://circ.ahajournals.org/content/1/4/502	Palliative		Not Provided 504	Thiomerin Approved Use Unknown

PubMed

Title	Date	PubMed
The subcutaneous administration of mercaptomerin; effective mercurial diuretic for the treatment of congestive heart failure.	1949 Aug 20	18137278

Name

Type

Language

MERCAPTOMERIN

Official Name

English

MERCURATE(2-), (3-(((3-CARBOXYLATO-2,2,3-TRIMETHYLCYCLOPENTYL)CARBONYL)AMINO)-2-METHOXYPROPYL)(2-(MERCAPTO-.KAPPA.S)ACETATO(2-)-.KAPPA.O)-, HYDROGEN (1:2), (T-4)-

Common Name

English

Mercaptomerin [WHO-DD]

Common Name

English

THIOMERIN

Brand Name

English

(T-4)-(3-(((3-CARBOXYLATO-2,2,3-TRIMETHYLCYCLOPENTYL)CARBONYL)AMINO)-2-METHOXYPROPYL)(MERCAPTOACETATO(2-)-O,S)MERCURATE(2-)

Common Name

English

MERCAPTOMERIN [HSDB]

Common Name

English

mercaptomerin [INN]

Common Name

English

DIUCARDYN

Brand Name

English

Code System Code Type Description

CAS

20223-84-1