Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H7NO4 |
| Molecular Weight | 205.1669 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=CC(O)=C2C=CC=C(O)C2=N1
InChI
InChIKey=FBZONXHGGPHHIY-UHFFFAOYSA-N
InChI=1S/C10H7NO4/c12-7-3-1-2-5-8(13)4-6(10(14)15)11-9(5)7/h1-4,12H,(H,11,13)(H,14,15)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. | 2010-05 |
|
| Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality. | 2010-03 |
|
| Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. | 2010-02 |
|
| A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies. | 2010-01-29 |
|
| The coming-out of malaria gametocytes. | 2010 |
|
| Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei. | 2009-12 |
|
| Vital role for the Plasmodium actin capping protein (CP) beta-subunit in motility of malaria sporozoites. | 2009-12 |
|
| Characterization of Plasmodium falciparum calcium-dependent protein kinase 4. | 2009-12 |
|
| A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. | 2009-09 |
|
| Cloning and molecular characterization of tick kynurenine aminotransferase (HlKAT) from Haemaphysalis longicornis (Acari: Ixodidae). | 2009-09 |
|
| An essential role for the Plasmodium Nek-2 Nima-related protein kinase in the sexual development of malaria parasites. | 2009-07-31 |
|
| Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry. | 2009-05 |
|
| Combination of 1H nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry with pattern recognition techniques for evaluation of metabolic profile associated with albuminuria. | 2009-04 |
|
| Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease. | 2009-04 |
|
| Trypanosoma brucei brucei: effects of ferrous iron and heme on ecto-nucleoside triphosphate diphosphohydrolase activity. | 2009-02 |
|
| Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | 2009-01-08 |
|
| Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. | 2009-01 |
|
| Photoactivity of kynurenine-derived UV filters. | 2008-12-11 |
|
| Involvement of ST1B subfamily of cytosolic sulfotransferase in kynurenine metabolism to form natriuretic xanthurenic acid sulfate. | 2008-12 |
|
| Analysis of urinary aromatic acids by liquid chromatography tandem mass spectrometry. | 2008-12 |
|
| Reverse genetics screen identifies six proteins important for malaria development in the mosquito. | 2008-10 |
|
| Characterization of the 3-HKT gene in important malaria vectors in India, viz: Anopheles culicifacies and Anopheles stephensi (Diptera: Culicidae). | 2008-09 |
|
| Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. | 2008-07 |
|
| Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. | 2008-06-03 |
|
| Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. | 2008-05-28 |
|
| Xanthurenic acid distribution, transport, accumulation and release in the rat brain. | 2008-05 |
|
| Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model. | 2008-04 |
|
| Genome-wide detection of serpentine receptor-like proteins in malaria parasites. | 2008-03-26 |
|
| Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance. | 2008-02-08 |
|
| Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25. | 2008-01-14 |
|
| Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. | 2008 |
|
| Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development. | 2007-12 |
|
| The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. | 2007-12 |
|
| Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation. | 2007-09 |
|
| Minimum requirements for ookinete to oocyst transformation in Plasmodium. | 2007-09 |
|
| Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold. | 2007-07-02 |
|
| Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans. | 2007-07 |
|
| Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase. | 2007-04 |
|
| The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. | 2007-03 |
|
| An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. | 2007-01-04 |
|
| Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. | 2006-12-01 |
|
| Prooxidant action of xanthurenic acid and quinoline compounds: role of transition metals in the generation of reactive oxygen species and enhanced formation of 8-hydroxy-2'-deoxyguanosine in DNA. | 2006-08 |
|
| Melatonin in Alzheimer's disease and other neurodegenerative disorders. | 2006-05-04 |
|
| The effects of blood feeding and exogenous supply of tryptophan on the quantities of xanthurenic acid in the salivary glands of Anopheles stephensi (Diptera: Culicidae). | 2006-03-24 |
|
| Plasmodium development in white-eye (kh(w)) and transformed strains (kh43) of Aedes aegypti (Diptera: Culicidae). | 2006-03 |
|
| [Metabolite fingerprint and biomarkers identification of rat urine after dosed with ginsenoside Rg3 based on ultra high performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)]. | 2006-01 |
|
| The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like beta-grasp domains. | 2006 |
|
| Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase. | 2005-11 |
|
| Effects of some naturally occurring iron ion chelators on in vitro superoxide radical formation. | 2005 |
|
| Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. | 2005 |
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| Code System | Code | Type | Description | ||
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DTXSID90207728
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C028330
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200-410-1
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401570
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58LAB1BG8J
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59-00-7
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m11536
Created by
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PRIMARY | Merck Index | ||
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XANTHURENIC ACID
Created by
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5699
Created by
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SUBSTANCE RECORD
