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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H12FNO3
Molecular Weight 212.2081
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of D-FLUOROMETHYLTYROSINE F-18

SMILES

N[C@H](CC1=CC=C(OC[18F])C=C1)C(O)=O

InChI

InChIKey=GEBHVOHKNWLITQ-DEVVULMSSA-N
InChI=1S/C10H12FNO3/c11-6-15-8-3-1-7(2-4-8)5-9(12)10(13)14/h1-4,9H,5-6,12H2,(H,13,14)/t9-/m1/s1/i11-1

HIDE SMILES / InChI
BAY-86-9596 (D-18F-FMT, or O-18F-fluoromethyl-D-tyrosine) was developed as an agent not only for tumor detection but also for monitoring early-phase response to radiation therapy by positron emission tomography (PET). This drug participated in clinical trials for patients with inflammation and solid tumors, but further information about trials is not available.

Approval Year

PubMed

PubMed

TitleDatePubMed
Evaluation of D-18F-FMT, 18F-FDG, L-11C-MET, and 18F-FLT for monitoring the response of tumors to radiotherapy in mice.
2009 Feb

Sample Use Guides

Cancer patients, single intravenous bolus injection of 300 MBq BAY 86-9596 on day one of the treatment period, PET/CT.
Route of Administration: Intravenous
Name Type Language
D-FLUOROMETHYLTYROSINE F-18
Common Name English
BAY-86-9596
Code English
BAY-86-9596 F-18
Code English
(F18)-D-FMT
Common Name English
(18F)D-FMT
Common Name English
BAY-869596-
Code English
BAY 86-9596
Code English
BAY-869596
Code English
J2.566.882K
Code English
(D)-18F-FLUOROMETHYLTYROSINE
Common Name English
(R)-2-AMINO-3-(4-18F-FLUOROMETHOXYPHENYL)- PROPIONIC ACID
Systematic Name English
BAY86-9596
Code English
D-(18F)FMT
Common Name English
(2R)-2-AMINO-3-(4-(FLUORANYLMETHOXY)PHENYL)PROPANOIC ACID
Systematic Name English
D-TYROSINE, O-(FLUORO-18F-METHYL)-
Common Name English
Code System Code Type Description
DRUG BANK
DB15296
Created by admin on Sat Dec 16 10:14:07 GMT 2023 , Edited by admin on Sat Dec 16 10:14:07 GMT 2023
PRIMARY
CAS
870452-26-9
Created by admin on Sat Dec 16 10:14:07 GMT 2023 , Edited by admin on Sat Dec 16 10:14:07 GMT 2023
PRIMARY
PUBCHEM
11579379
Created by admin on Sat Dec 16 10:14:07 GMT 2023 , Edited by admin on Sat Dec 16 10:14:07 GMT 2023
PRIMARY
SMS_ID
300000041416
Created by admin on Sat Dec 16 10:14:07 GMT 2023 , Edited by admin on Sat Dec 16 10:14:07 GMT 2023
PRIMARY
FDA UNII
58HVN5SR99
Created by admin on Sat Dec 16 10:14:07 GMT 2023 , Edited by admin on Sat Dec 16 10:14:07 GMT 2023
PRIMARY