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Details

Stereochemistry ACHIRAL
Molecular Formula Fe
Molecular Weight 58.9349
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of FERROUS CATION FE-59

SMILES

[Fe+2]

InChI

InChIKey=CWYNVVGOOAEACU-AKLPVKDBSA-N
InChI=1S/Fe/q+2/i1+3

HIDE SMILES / InChI

Description
Curator's Comment:: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/2330802 | https://www.ncbi.nlm.nih.gov/pubmed/5098207

Ferrous citrate Fe 59 is indicated, by intravenous administration, to determine various parameters of the kinetics of iron metabolism, including plasma iron clearance, plasma iron turnover rate, and the utilization of iron in new red blood cells. The values of serum iron obtained from these studies provide diagnostic information in patients with anemias. Ferrous citrate Fe 59 is also useful to assess the role of the spleen in red blood cell production and destruction, and thus to help determine the advisability of splenectomy. Also, organ uptake measurements are used to measure the sites of red cell production (or lack thereof) in extramedullary erythropoiesis in myeloproliferative disorders. Iron from ferrous citrate is bound to plasma protein (transferrin) and carried to the blood-forming organs where it is utilized to form hemoglobin or is deposited in the reticuloendothelial cells of the liver and spleen. The amount of radioactive iron absorbed, transported, stored, utilized, and excreted can then be measured by the periodic collection of blood specimens and external counting.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
FERROUS CITRATE FE 59

Approved Use

It was used for anemia diagnosis.

Launch Date

1.24847997E11
Diagnostic
FERROUS CITRATE FE 59

Approved Use

Unknown

Launch Date

1.24934398E11
PubMed

PubMed

TitleDatePubMed
Effect of anticholinergic agents on the intestinal absorption of 59 Fe ferrous citrate.
1971 Sep
Patents

Patents

Sample Use Guides

Intravenous or oral, 0.185 to 0.555 megabecquerel (5 to 15 microcuries).
Route of Administration: Other
In Vitro Use Guide
Unknown
Name Type Language
FERROUS CATION FE-59
Common Name English
IRON II FE-59
Common Name English
FERROUS ION FE-59
Common Name English
FE-59
Common Name English
Code System Code Type Description
FDA UNII
5634T58D89
Created by admin on Sat Jun 26 14:39:12 UTC 2021 , Edited by admin on Sat Jun 26 14:39:12 UTC 2021
PRIMARY
PUBCHEM
73952216
Created by admin on Sat Jun 26 14:39:12 UTC 2021 , Edited by admin on Sat Jun 26 14:39:12 UTC 2021
PRIMARY