| Stereochemistry | ABSOLUTE |
| Molecular Formula | 4C4H5NO4.2K.Mg.4H |
| Molecular Weight | 630.8806 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H+].[H+].[H+].[H+].[Mg++].[K+].[K+].N[C@@H](CC([O-])=O)C([O-])=O.N[C@@H](CC([O-])=O)C([O-])=O.N[C@@H](CC([O-])=O)C([O-])=O.N[C@@H](CC([O-])=O)C([O-])=O
InChI
InChIKey=LVBRFZFUCKKGDJ-HJWRJIQTSA-J
InChI=1S/4C4H7NO4.2K.Mg/c4*5-2(4(8)9)1-3(6)7;;;/h4*2H,1,5H2,(H,6,7)(H,8,9);;;/q;;;;2*+1;+2/p-4/t4*2-;;;/m0000.../s1
Potassium magnesium aspartate (K,Mg aspartate) is used in treating and preventing cardiac disruptions caused by electrolytic disturbances, primarily low potassium (K) and magnesium (Mg) levels (e.g. in the treatment with cardiac glycosides and diuretic drugs). It is used as a mineral supplement. The proposed mechanisms of action of magnesium-potassium aspartate include:
Stabilization of cellular membranes by normalization of the levels of magnesium and potassium in the cells.
Detoxification of ammonia or increase in the tricarboxylic acid-cycle flux. As increased levels of ammonia and depleted levels of potassium and magnesium ions in the plasma are associated with exercise-induced fatigue, this combination of aspartate (which detoxifies ammonia) and magnesium and potassium is particularly relevant in sports nutrition. Potassium magnesium aspartate is reported as an ingredient of Aspara in Japan, Panangin in Russian Federation, Bulgaria, China, Hungary, Romania etc., Asparkam in Georgia. Trophicard in Germany.
Approval Year
PubMed
Patents
Sample Use Guides
Take 1-2 tablets three times a day, but not more than 3 tablets per reception after a meal, because fasting gastric contents reduces the effectiveness of the drug. Duration of application and the need for repeated applications are defined individually.
Injections
Applied intravenous drip infusion in a slow injection (~ 20 drops of 1 minute) of 1-2 ampoules of drug is dissolved in 50-100 ml glucose solution or 5% dextrose. Reintroducing - no earlier than 4-6 hours after the first drip.
main substances (1 tablet and 1 vial, respectively):
166,3 mg of potassium aspartate;
175 mg of magnesium aspartate.
452 mg of potassium aspartate;
400 mg of magnesium aspartate.
Route of Administration:
Other
SUBSTANCE RECORD
