Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H28N6O |
| Molecular Weight | 368.4759 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H](CO)NC1=NC2=C(N=CN2C(C)C)C(=N1)N(C)CC3=CC=CC=C3
InChI
InChIKey=YPYWONAECUVKHY-MRXNPFEDSA-N
InChI=1S/C20H28N6O/c1-5-16(12-27)22-20-23-18(25(4)11-15-9-7-6-8-10-15)17-19(24-20)26(13-21-17)14(2)3/h6-10,13-14,16,27H,5,11-12H2,1-4H3,(H,22,23,24)/t16-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative. | 2015 |
|
| Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease? | 2013 |
|
| Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action. | 2012-12 |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
866893-90-5
Created by
admin on Wed Apr 02 06:35:08 GMT 2025 , Edited by admin on Wed Apr 02 06:35:08 GMT 2025
|
PRIMARY | |||
|
5289296
Created by
admin on Wed Apr 02 06:35:08 GMT 2025 , Edited by admin on Wed Apr 02 06:35:08 GMT 2025
|
PRIMARY | |||
|
5563QWW82B
Created by
admin on Wed Apr 02 06:35:08 GMT 2025 , Edited by admin on Wed Apr 02 06:35:08 GMT 2025
|
PRIMARY |
SUBSTANCE RECORD
