AZIRIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H5N
Molecular Weight	43.0678
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CN1

InChI

InChIKey=NOWKCMXCCJGMRR-UHFFFAOYSA-N

InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Immobilized liposome layers for drug delivery applications: inhibition of angiogenesis.	2002-04-23	11943397
Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides.	2002-04-05	11933220
Highly diastereoselective aziridination of imines with trimethylsilyldiazomethane. Subsequent silyl substitution with electrophiles, ring opening, and metalation of C-silylaziridines--a cornucopia of highly selective transformations.	2002-04-05	11925250
Enantioselective aziridination of alkenes with N-aminophthalimide in the presence of lead tetraacetate-mediated chiral ligand.	2002-04-04	11922794
Structure and electrochemistry of self-organized fullerene-lipid bilayer films.	2002-04-02	11933092
Metalloporphyrin-mediated asymmetric nitrogen-atom transfer to hydrocarbons: aziridination of alkenes and amidation of saturated C-H bonds catalyzed by chiral ruthenium and manganese porphyrins.	2002-04-02	11933085
Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation.	2002-04	11945074
Gene delivery to the lung using protein/polyethylenimine/plasmid complexes.	2002-04	11938461
Interactions of aziridines with nickel complexes: oxidative-addition and reductive-elimination reactions that break and make C-N bonds.	2002-03-27	11902877
A method for the parallel synthesis of multiply substituted oxazolidinones.	2002-03-12	11886291
Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes.	2002-03	11920765
Syntheses of 1beta-methylcarbapenems bearing 5-methyl-4-hydroxypyrrolidinone.	2002-03	11911211
Studies on enhancement of Cr(VI) biosorption by chemically modified biomass of Rhizopus nigricans.	2002-03	11902777
Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector.	2002-03	11896442
Regioselective and stereoselective nucleophilic ring opening reactions of a phenyl-substituted aziridine: enantioselective synthesis of beta-substituted tryptophan, cysteine, and serine derivatives.	2002-02-22	11846696
2H-Azirine 3-phosphonates: a new class of chiral iminodienophiles. Asymmetric synthesis of quaternary piperidine phosphonates.	2002-02-21	11843615
Solution- and solid-phase synthesis of 4-hydroxy-4,5-dihydroisoxazole derivatives from enantiomerically pure N-tosyl-2,3-aziridine alcohols.	2002-02-21	11843575
A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes.	2002-02-19	11853937
Optimization of factors influencing the transfection efficiency of folate-PEG-folate-graft-polyethylenimine.	2002-02-19	11853936
Polyethylenimine-mediated suicide gene transfer induces a therapeutic effect for hepatocellular carcinoma in vivo by using an Epstein-Barr virus-based plasmid vector.	2002-02-15	11829460
DNA cross-linking by azinomycin B: Monte Carlo simulations in the evaluation of sequence selectivity.	2002-02-14	11831897
Process for the preparation of pathogen-inactivated RBC concentrates by using PEN110 chemistry: preclinical studies.	2002-02	11896326
Preferential transfection of adult mouse neural stem cells and their immediate progeny in vivo with polyethylenimine.	2002-02	11860270
Non-viral gene delivery to atelectatic and ventilated lungs.	2002-02	11845855
New basic membrane-destabilizing peptides for plasmid-based gene delivery in vitro and in vivo.	2002-02	11829517
Host selection as a downstream strategy: polyelectrolyte precipitation of beta-glucuronidase from plant extracts.	2002-01-20	11753921
Integrity of GH-loop of foot-and-mouth disease virus during virus inactivation: detection by epitope specific antibodies.	2002-01-15	11803078
Diamine synthesis: exploring the regioselectivity of ring opening of aziridinium ions.	2002-01-11	11777478
A powerful cooperative interaction between a fusogenic peptide and lipofectamine for the enhancement of receptor-targeted, non-viral gene delivery via integrin receptors.	2002-01-10	11778902
Total synthesis of epi-7-deoxypancratistatin via aza-Payne rearrangement and intramolecular cyclization.	2002-01-10	11772104
Ultrafast sodium dodecyl sulfate micellar electrokinetic chromatography with very acidic running buffers.	2002-01-01	11795804
Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation.	2002-01	11786049
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine.	2001-11-22	11716690
2-Benzyl-3,4-iminobutanoic acid as inhibitor of carboxypeptidase A.	2001-11-19	11677137
Inactivation of viruses by aziridines.	2001-11-12	11672893
Efficient gene delivery via non-covalent complexes of folic acid and polyethylenimine.	2001-11-09	11689266
The selection of a commercial route for the D1 antagonist Sch-39166.	2001-11	11899619
A theoretical study of neighboring-group participation in thione-to-thiol rearrangement of xanthates. molecular orbital calculation using a conductor-like screening model (COSMO) approach.	2001-11	11724233
Adenovirus hexon protein enhances nuclear delivery and increases transgene expression of polyethylenimine/plasmid DNA vectors.	2001-11	11708884
Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity.	2001-10-25	11606119
Maintenance of nonviral vector particle size during the freezing step of the lyophilization process is insufficient for preservation of activity: insight from other structural indicators.	2001-10	11745704
Prolonged organ retention and safety of plasmid DNA administered in polyethylenimine complexes.	2001-10	11704820
Liquid chromatographic determination of total and beta-N-oxalyl-L-alpha,beta-diaminopropionic acid in lathyrus sativus seeds using both refractive index and bioelectrochemical detection.	2001-09-21	11594394
Synthesis, in vitro metabolic studies, and antitumour activity of methyl analogues of ifosfamide.	2001-09	11688140
Enhanced gene transfection in macrophages using mannosylated cationic liposome-polyethylenimine-plasmid DNA complexes.	2001-06	11697205
Cost-effective whole-cell assay for laboratory evolution of hydroxylases in Escherichia coli.	2001-04	11689105
Consecutive carbon-carbon bond formation approach in tandem cyclization reactions.	2001	11933248
Molecular modeling and 3D-QSAR studies in 2-aziridinyl-and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives as potential antimalarial agents.	2001	11813805
Poly(amidoamine)s as potential nonviral vectors: ability to form interpolyelectrolyte complexes and to mediate transfection in vitro.	2001	11710005
Role of cholinergic mossy fibers in vestibular nuclei in the development of vestibular compensation.	2001	11677719

Patents

Name

Type

Language

AZIRIDINE

Systematic Name

English

ETHYLENEIMINE

Preferred Name

English

ETHYLENIMINE

Common Name

English

ETHYLENEIMINE [HSDB]

Common Name

English

ETHYLENIMINE [MI]

Common Name

English

AZIRIDINE [IARC]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C292