U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C27H29NO10
Molecular Weight 527.5199
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIROZADIL

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)OCC2=CC=CC(COC(=O)C3=CC(OC)=C(OC)C(OC)=C3)=N2

InChI

InChIKey=DIIBXMIIOQXTHW-UHFFFAOYSA-N
InChI=1S/C27H29NO10/c1-31-20-10-16(11-21(32-2)24(20)35-5)26(29)37-14-18-8-7-9-19(28-18)15-38-27(30)17-12-22(33-3)25(36-6)23(13-17)34-4/h7-13H,14-15H2,1-6H3

HIDE SMILES / InChI
Pirozadil (Pemix), a hypolipidemic agent that improves cerebral blood flow and Inhibits platelet aggregation. This drug was studied for the treatment of patients with Type IIa hyperlipoproteinemia.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Clinical pharmacology of pirozadil].
1982 Oct 15
[Antiplatelet action of pirozadil].
1984 Feb 18
[Efficacy and tolerance to pirozadil over a long term. Drug surveillance study. The Pirozadil Drug Surveillance Group].
1987 Dec 12

Sample Use Guides

1.5 to 2 g/day of pirozadil
Route of Administration: Oral
Name Type Language
PIROZADIL
INN   MART.   MI   WHO-DD  
INN  
Official Name English
pirozadil [INN]
Common Name English
Pirozadil [WHO-DD]
Common Name English
PIROZADIL [MI]
Common Name English
PIROZADIL [MART.]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C98151
Created by admin on Fri Dec 15 15:48:48 GMT 2023 , Edited by admin on Fri Dec 15 15:48:48 GMT 2023
Code System Code Type Description
MERCK INDEX
m8890
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PRIMARY Merck Index
EVMPD
SUB09939MIG
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PRIMARY
ChEMBL
CHEMBL2106888
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PRIMARY
NCI_THESAURUS
C66435
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PRIMARY
INN
3754
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FDA UNII
54978VNA4T
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DRUG CENTRAL
2212
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PUBCHEM
68711
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SMS_ID
100000081680
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EPA CompTox
DTXSID70202458
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ECHA (EC/EINECS)
258-978-1
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MESH
C015453
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PRIMARY
CAS
54110-25-7
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