PIROZADIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H29NO10
Molecular Weight	527.5199
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PIROZADIL

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)OCC2=CC=CC(COC(=O)C3=CC(OC)=C(OC)C(OC)=C3)=N2

InChI

InChIKey=DIIBXMIIOQXTHW-UHFFFAOYSA-N

InChI=1S/C27H29NO10/c1-31-20-10-16(11-21(32-2)24(20)35-5)26(29)37-14-18-8-7-9-19(28-18)15-38-27(30)17-12-22(33-3)25(36-6)23(13-17)34-4/h7-13H,14-15H2,1-6H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2704867 | https://www.ncbi.nlm.nih.gov/pubmed/3435604

Pirozadil (Pemix), a hypolipidemic agent that improves cerebral blood flow and Inhibits platelet aggregation. This drug was studied for the treatment of patients with Type IIa hyperlipoproteinemia.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Clinical pharmacology of pirozadil].	1982 Oct 15	7178579
[Antiplatelet action of pirozadil].	1984 Feb 18	6708647
[Efficacy and tolerance to pirozadil over a long term. Drug surveillance study. The Pirozadil Drug Surveillance Group].	1987 Dec 12	3448438

Sample Use Guides

In Vivo Use Guide

1.5 to 2 g/day of pirozadil

Route of Administration: Oral

Name

Type

Language

PIROZADIL

Official Name

English

pirozadil [INN]

Common Name

English

Pirozadil [WHO-DD]

Common Name

English

PIROZADIL [MI]

Common Name

English

PIROZADIL [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C98151

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

Code System Code Type Description

MERCK INDEX

m8890

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Merck Index

EVMPD

SUB09939MIG

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ChEMBL

CHEMBL2106888

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NCI_THESAURUS

C66435

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INN

3754

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FDA UNII

54978VNA4T

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DRUG CENTRAL

2212

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PUBCHEM

68711

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SMS_ID

100000081680

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

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EPA CompTox

DTXSID70202458

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

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ECHA (EC/EINECS)

258-978-1

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

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MESH

C015453

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

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CAS

54110-25-7

Created by admin on Fri Dec 15 15:48:48 UTC 2023 , Edited by admin on Fri Dec 15 15:48:48 UTC 2023

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ACTIVE MOIETY


					54978VNA4T

PIROZADIL