Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C29H40O5S |
| Molecular Weight | 500.69 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 8 / 8 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CSC4=CC=CC(CO)=C4
InChI
InChIKey=KELRBTWVTDHIHS-KGTFJIFRSA-N
InChI=1S/C29H40O5S/c1-6-27(4)15-23(34-24(32)17-35-21-9-7-8-20(14-21)16-30)28(5)18(2)10-12-29(19(3)26(27)33)13-11-22(31)25(28)29/h6-9,14,18-19,23,25-26,30,33H,1,10-13,15-17H2,2-5H3/t18-,19+,23-,25+,26+,27-,28+,29+/m1/s1
Approval Year
| Name | Type | Language | ||
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Preferred Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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548N5X8LTS
Created by
admin on Tue Apr 01 17:02:15 GMT 2025 , Edited by admin on Tue Apr 01 17:02:15 GMT 2025
|
PRIMARY | |||
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BC-7013
Created by
admin on Tue Apr 01 17:02:15 GMT 2025 , Edited by admin on Tue Apr 01 17:02:15 GMT 2025
|
PRIMARY | Pleuromutilins were discovered as natural-product antibiotics in 1950. Tiamulin was the first pleuromutilin compound to be approved for veterinary use in 1979, followed by valnemulin in 1999.Most pleuromutilins have an antibacterial spectrum that spans the common pathogens involved in both skin and respiratory tract infections. Two new pleuromutilins, BC-3205 and BC-7013 (both Nabriva Therapeutics AG), have entered clinical trials. In this review, the key properties of pleuromutilin derivatives, designed primarily through modifications at the C(14) side chain, are presented, and the potential of these compounds in systemic therapy in humans is discussed. BC7013 belongs to a series of proprietary Nabriva pleuromutilins, which have been designed by Nabrivas medicinal chemists to fulfill the specific requirements of a topical antibacterial agent. The clinical study is designed to evaluate safety and tolerability of BC7013. | ||
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16656782
Created by
admin on Tue Apr 01 17:02:15 GMT 2025 , Edited by admin on Tue Apr 01 17:02:15 GMT 2025
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PRIMARY | |||
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1028291-66-8
Created by
admin on Tue Apr 01 17:02:15 GMT 2025 , Edited by admin on Tue Apr 01 17:02:15 GMT 2025
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PRIMARY |
ACTIVE MOIETY
