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Details

Stereochemistry RACEMIC
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity ( + / - )
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1'',3A-DI-EPI-PERINDOPRIL, (±)-

SMILES

CCC[C@@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

InChIKey=IPVQLZZIHOAWMC-OTJKEOIZSA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13+,14+,15-,16-/m0/s1

HIDE SMILES / InChI

Description

(1''R,3AR)-1'',3A-di-epi-Perindopril is an epimer (S, RS, SR) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is much less active than the parent compound, perindopril.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
(±)-1'',3A-DI-EPI-PERINDOPRIL
Preferred Name English
1'',3A-DI-EPI-PERINDOPRIL, (±)-
Common Name English
PERINDOPRIL TERT-BUTYLAMINE IMPURITY Z [EP IMPURITY]
Common Name English
(2RS,3ASR,7ARS)-1-((2RS)-2-(((1SR)-1-(ETHOXYCARBONYL)BUTYL)AMINO)PROPANOYL)OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
Systematic Name English
Code System Code Type Description
FDA UNII
534X2137QC
Created by admin on Mon Mar 31 23:24:02 GMT 2025 , Edited by admin on Mon Mar 31 23:24:02 GMT 2025
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