Details
Stereochemistry | ACHIRAL |
Molecular Formula | C18H19NOS |
Molecular Weight | 297.415 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C(=S)OC1=CC=C2CCCC2=C1)C3=CC(C)=CC=C3
InChI
InChIKey=ANJNOJFLVNXCHT-UHFFFAOYSA-N
InChI=1S/C18H19NOS/c1-13-5-3-8-16(11-13)19(2)18(21)20-17-10-9-14-6-4-7-15(14)12-17/h3,5,8-12H,4,6-7H2,1-2H3
DescriptionCurator's Comment: Description was created using several sources including:
https://www.google.com/patents/US3509200; http://www.trademarkia.com/dalnate-72412220.html; http://www.druglead.com/cds/tolindate.html;
http://jurbase.ru/postr/docum51/part6.htm
Curator's Comment: Description was created using several sources including:
https://www.google.com/patents/US3509200; http://www.trademarkia.com/dalnate-72412220.html; http://www.druglead.com/cds/tolindate.html;
http://jurbase.ru/postr/docum51/part6.htm
Tolindate, a thiocarbamate, is a synthetic antifungal approved by FDA as an over-the-counter (OTC) drug product and is marketed by Norcliff Thayer Inc. It was prepared by treating 5-indanyl thionochloroformate with N-methyl-m-toluidine and patented in 1970 by USV Pharmaceutical Corporation tas a compound with strong topical antifungal activity that may be administered topically in the form of ointments and solutions. It was used in eastern Europe as Dalnate (USV Pharmaceutical Corporation trademark registerd in 6/26/1973) for topical application in the treatment of various dermatoses. Produced by ZORKA Pharma (at present Hemofarm a.d., Serbia) topical cream or solution Dalnate was registered for marketing in Russia.
Originator
Sources: https://www.google.com/patents/US3509200
Curator's Comment: Was patented in 1970
Approval Year
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NCI_THESAURUS |
C514
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m10945
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C84218
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ACTIVE MOIETY