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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H23NO4
Molecular Weight 341.4009
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THEBACON

SMILES

COC1=C2O[C@H]3C(OC(C)=O)=CC[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C

InChI

InChIKey=RRJQTGHQFYTZOW-ILWKUFEGSA-N
InChI=1S/C20H23NO4/c1-11(22)24-16-7-5-13-14-10-12-4-6-15(23-3)18-17(12)20(13,19(16)25-18)8-9-21(14)2/h4,6-7,13-14,19H,5,8-10H2,1-3H3/t13-,14+,19-,20-/m0/s1

HIDE SMILES / InChI

Description

Thebacon (dihydrocodeinone enol acetate, trade name Acedicon) is semisynthetic opioid analgetic and antitussive compound. Boehringer-Ingelheim merketed Acedicon for the treatment of cough. Thebacon is a Schedule I drug, that has not got approved use in US.

CNS Activity

CNS Active
4,002

Originator

Boehringer Ingelheim
130

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
Carboxylesterase 2
9
Substrate
661

Conditions

ConditionModalityTargetsHighest PhaseProduct
Cough
106
 Primary
Approved
8,583
ACEDICON

PubMed

Patents

US1731152
2

Sample Use Guides

In Vivo Use Guide
7.5-15 mg per day
Route of Administration: Other
In Vitro Use Guide
Unknown
ACTIVE MOIETY
Structure of THEBACON
NIH
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