U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C53H100N16O13
Molecular Weight 1169.4605
Optical Activity UNSPECIFIED
Defined Stereocenters 13 / 13
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COLISTIN A

SMILES

[H][C@]1(NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC(=O)[C@H](CCNC1=O)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)CCCC[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O

InChI

InChIKey=XDJYMJULXQKGMM-HHAJOKTESA-N
InChI=1S/C53H100N16O13/c1-9-30(6)12-10-11-13-41(72)60-33(14-20-54)48(77)69-43(32(8)71)53(82)65-36(17-23-57)45(74)64-38-19-25-59-52(81)42(31(7)70)68-49(78)37(18-24-58)62-44(73)34(15-21-55)63-50(79)39(26-28(2)3)67-51(80)40(27-29(4)5)66-46(75)35(16-22-56)61-47(38)76/h28-40,42-43,70-71H,9-27,54-58H2,1-8H3,(H,59,81)(H,60,72)(H,61,76)(H,62,73)(H,63,79)(H,64,74)(H,65,82)(H,66,75)(H,67,80)(H,68,78)(H,69,77)/t30-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40+,42-,43-/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Case report: greater meningeal inflammation in lumbar than in ventricular region in human bacterial meningitis.
2004 Dec
Spray-dried plasma improves growth performance and reduces inflammatory status of weaned pigs challenged with enterotoxigenic Escherichia coli K88.
2004 Jun
Characterization and antibiotic susceptibility of Listeria monocytogenes isolated from poultry and red meat in Morocco.
2008
[Diagnostic and therapeutic management of Gram-negative infections].
2008 Apr
[Inhaled therapies in cystic fibrosis].
2008 Oct
Oropharyngeal decontamination in intensive care patients: less is not more.
2009
The food contaminant fumonisin B(1) reduces the maturation of porcine CD11R1(+) intestinal antigen presenting cells and antigen-specific immune responses, leading to a prolonged intestinal ETEC infection.
2009 Jul-Aug
Prevalence and diversity of integrons and associated resistance genes in Escherichia coli isolates from poultry meat in Tunisia.
2009 Nov
Genotyping of Streptococcus agalactiae (group B streptococci) isolated from vaginal and rectal swabs of women at 35-37 weeks of pregnancy.
2009 Sep 11
Comparison of different sampling techniques and of different culture methods for detection of group B streptococcus carriage in pregnant women.
2010 Sep 29
Patents
Name Type Language
COLISTIN A
MI  
Common Name English
COLISTIN A [MI]
Common Name English
POLYMYXIN E1
Common Name English
Colistin a [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C78160
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
Code System Code Type Description
PUBCHEM
24825758
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY
CHEBI
59064
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY
MERCK INDEX
m3733
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY Merck Index
FDA UNII
500HI50Z9H
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY
CAS
7722-44-3
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY
NCI_THESAURUS
C75972
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY
EPA CompTox
DTXSID5049079
Created by admin on Fri Dec 15 15:56:51 GMT 2023 , Edited by admin on Fri Dec 15 15:56:51 GMT 2023
PRIMARY