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Details

Stereochemistry ACHIRAL
Molecular Formula C19H18N2O3
Molecular Weight 322.3578
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KEBUZONE

SMILES

CC(=O)CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=LGYTZKPVOAIUKX-UHFFFAOYSA-N
InChI=1S/C19H18N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,17H,12-13H2,1H3

HIDE SMILES / InChI

Description

Kebuzone is a cyclooxygenase inhibitor that was used for the treatment of different inflammatory conditions such as thrombophlebitis and rheumatoid arthritis. The current marketing status of the drug is unknown and supposed to be discontinued.

Approval Year

Unknown
139,594

Targets

Primary TargetPharmacologyConditionPotency
Cyclooxygenase
89
Inhibitor
8,297

Conditions

ConditionModalityTargetsHighest PhaseProduct
Thrombophlebitis
3
 Palliative
Approved
8,429
KETAZON
Musculoskeletal disorders
10
 Palliative
Approved
8,429
KETAZON

PubMed

Patents

WO2007128412 A1
1

Sample Use Guides

In Vivo Use Guide
1 (250 mg) to 2 dragees 3 times daily
Route of Administration: Oral
In Vitro Use Guide
Unknown
ACTIVE MOIETY
Structure of KEBUZONE
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