NIFURATRONE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8N2O5
Molecular Weight	200.1488
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of NIFURATRONE

Structure Search

SMILES

OCC\[N+]([O-])=C\C1=CC=C(O1)[N+]([O-])=O

InChI

InChIKey=QSWZUVFMUIEHAG-YVMONPNESA-N

InChI=1S/C7H8N2O5/c10-4-3-8(11)5-6-1-2-7(14-6)9(12)13/h1-2,5,10H,3-4H2/b8-5-

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4939734 | https://www.ncbi.nlm.nih.gov/pubmed/5053162 | https://www.ncbi.nlm.nih.gov/pubmed/5521345

Nifuratrone is a nitrofuran which was used for the control of Salmonella choleraesuis in swine. It was also used for the treatment of gonorrhea.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Nifuratrone, a new nitrofuran: in vitro and in vivo activities.	1970	4939734
Nifuratrone and gonorrhea.	1970	5521345
Nifuratrone, a new nitrofuran for the control of Salmonella choleraesuis in swine.	1972 Sep	5053162

Sample Use Guides

In Vivo Use Guide

Gilts were given single oral doses of nifuratrone at a level of 6 or 12 mg/kg body weight.

Route of Administration: Oral

Name

Type

Language

NIFURATRONE

Official Name

English

nifuratrone [INN]

Common Name

English

N-(2-Hydroxyethyl)-α-(5-nitro-2-furyl)nitrone

Common Name

English

NSC-303603

Code

English

NIFURATRONE [USAN]

Common Name

English

ETHANOL, 2-(((5-NITRO-2-FURANYL)METHYLENE)AMINO)-, N-OXIDE

Common Name

English

Code System Code Type Description

CAS

19561-70-7

Created by admin on Sat Dec 16 05:03:35 UTC 2023 , Edited by admin on Sat Dec 16 05:03:35 UTC 2023

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NSC

303603

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ChEMBL

CHEMBL2106512

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INN

2911

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PUBCHEM

5910161

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MESH

C001391

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NCI_THESAURUS

C166788

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SMS_ID

100000083869

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EPA CompTox

DTXSID501043200

Created by admin on Sat Dec 16 05:03:35 UTC 2023 , Edited by admin on Sat Dec 16 05:03:35 UTC 2023

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EVMPD

SUB09262MIG

Created by admin on Sat Dec 16 05:03:35 UTC 2023 , Edited by admin on Sat Dec 16 05:03:35 UTC 2023

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FDA UNII

4V8564T36O

Created by admin on Sat Dec 16 05:03:35 UTC 2023 , Edited by admin on Sat Dec 16 05:03:35 UTC 2023

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ACTIVE MOIETY


					4V8564T36O