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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H20N4O7
Molecular Weight 332.3098
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TALO-ZANAMIVIR

SMILES

[H][C@]1(OC(=C[C@@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO

InChI

InChIKey=ARAIBEBZBOPLMB-PKGQWCBFSA-N
InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6-,8-,9-,10-/m1/s1

HIDE SMILES / InChI

Description

Talo-Zanamivir is inactive enantiomer of Zanamivir, a medication used to treat and prevent influenza caused by influenza A and B viruses. Talo-Zanamivir is used as internal standard for Zanamivir analytical studies.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
A structural and energetics analysis of the binding of a series of N-acetylneuraminic-acid-based inhibitors to influenza virus sialidase.
1996 Jun
Patents

Patents

20070225358
1
7468388
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
TALO-ZANAMIVIR
Common Name English
(2R,3R,4R)-3-(ACETYLAMINO)-4-CARBAMIMIDOYLAMINO-2-((1R,2R)-1,2,3-TRIHYDROXYPROPYL)-3,4-DIHYDRO-2H-PYRAN-6-CARBOXYLIC ACID
Systematic Name English
ZANAMIVIR HYDRATE IMPURITY H [EP IMPURITY]
Common Name English
D-GLYCERO-D-TALO-NON-2-ENONIC ACID, 5-(ACETYLAMINO)-4-((AMINOIMINOMETHYL)AMINO)-2,6-ANHYDRO-3,4,5-TRIDEOXY-
Systematic Name English
Code System Code Type Description
CAS
179531-57-8
Created by admin on Sat Dec 16 11:23:04 GMT 2023 , Edited by admin on Sat Dec 16 11:23:04 GMT 2023
PRIMARY
PUBCHEM
58974096
Created by admin on Sat Dec 16 11:23:04 GMT 2023 , Edited by admin on Sat Dec 16 11:23:04 GMT 2023
PRIMARY
FDA UNII
4T35I32653
Created by admin on Sat Dec 16 11:23:04 GMT 2023 , Edited by admin on Sat Dec 16 11:23:04 GMT 2023
PRIMARY
SUBSTANCE RECORD
Structure of TALO-ZANAMIVIR
NIH
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