DARENZEPINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H21N3O2
Molecular Weight	347.4103
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of DARENZEPINE

Structure Search

SMILES

CN1CCN(CC1)C(=O)\C=C2\C3=C(NC(=O)C4=C2C=CC=C4)C=CC=C3

InChI

InChIKey=VBQROPPRMFZXNC-NBVRZTHBSA-N

InChI=1S/C21H21N3O2/c1-23-10-12-24(13-11-23)20(25)14-18-15-6-2-3-8-17(15)21(26)22-19-9-5-4-7-16(18)19/h2-9,14H,10-13H2,1H3,(H,22,26)/b18-14+

HIDE SMILES / InChI

Description
Sources: https://www.sciencedirect.com/science/article/pii/S0065774308610362 | https://www.ncbi.nlm.nih.gov/pubmed/11814816

Darenzepine is an antagonist of muscarinic receptors, developed by at Knoll/BASF Pharma. It is claimed to have antiulcer effect superior to pirenzepine and to have less anticholinergic adverse effects.

Approval Year

Name

Type

Language

DARENZEPINE

Official Name

English

(E)-1-((5,6-DIHYDRO-6-OXO-11-MORPHANTHRIDINYLIDENE)ACETYL)-4-METHYLPIPERAZINE

Preferred Name

English

darenzepine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

Code System Code Type Description

EVMPD

SUB06911MIG

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

PRIMARY

INN

5597

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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ChEMBL

CHEMBL2106144

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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FDA UNII

4SDY4L68FP

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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EPA CompTox

DTXSID40904614

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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CAS

84629-61-8

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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NCI_THESAURUS

C76482

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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SMS_ID

100000083442

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

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PUBCHEM

9819661

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

PRIMARY

CAS

90274-22-9

Created by admin on Mon Mar 31 18:24:09 GMT 2025 , Edited by admin on Mon Mar 31 18:24:09 GMT 2025

SUPERSEDED

ACTIVE MOIETY


					4SDY4L68FP