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Details

Stereochemistry ACHIRAL
Molecular Formula C8H8O3
Molecular Weight 152.1473
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of P-ANISIC ACID

SMILES

COC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=ZEYHEAKUIGZSGI-UHFFFAOYSA-N
InChI=1S/C8H8O3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H,9,10)

HIDE SMILES / InChI

Description

SODIUM ANISATE is derived from fennel, this is the sodium salt of p-anisic acid. It is classified as antimicrobial and flavouring. It acts as an anti-fungal agent, and when paired with sodium levulinate the two ingredients make for a comprehensive preservative for cosmetics. This ingredient is approved for use in organic cosmetics. Sodium anisate (dermosoft® anisate) is an easy to use water soluble salt of an organic acid with an excellent fungicidal activity. It can be added to the cold or hot water phase at any step of the process. The combination with antimicrobial surface active substances or organic acids is recommended to improve the performance of the product even at higher pH.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
9.9 nM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Inactive ingredient
Thera Wise Natural Acne
PubMed

PubMed

TitleDatePubMed
Hypoglycemic activity of Hemidesmus indicus R. Br. on streptozotocin-induced diabetic rats.
2008 Jan
A novel norditerpenoid alkaloid from Aconitum macrorhynchum.
2009 Aug
Variations in IC(50) values with purity of mushroom tyrosinase.
2009 Sep 2
Tetra-kis(μ-4-methoxy-benzoato)bis-[(4-methoxy-benzoato)(1,10-phenan-throline)terbium(III)].
2009 Sep 26
Influence of very low doses of mediators on fungal laccase activity - nonlinearity beyond imagination.
2009 Sep 4
Bis(4-meth-oxy-benzoato)-κO,O';κO-bis-(nicotinamide-κN)zinc(II).
2010 Aug 21
2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
2010 Feb
Diaqua-bis-(4-meth-oxy-benzoato-κO)bis-(nicotinamide-κN)cobalt(II) dihydrate.
2010 Jul 10
N'-[Bis(benzyl-sulfan-yl)methyl-idene]-4-meth-oxy-benzohydrazide.
2010 Jul 3
Diaqua-bis-(4-meth-oxy-benzoato-κO)bis-(nicotinamide-κN)nickel(II) dihydrate.
2010 Jul 7
Di-μ-nicotinamide-κO:N;κN:O-bis-[aqua-bis-(4-meth-oxy-benzoato-κO)copper(II)].
2010 Jun 16
Diaqua-(isonicotinamide-κN)(4-meth-oxy-benzoato-κO,O')(4-meth-oxy-benzoato-κO)cobalt(II).
2010 Jun 16
Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris.
2010 Mar
Bis[μ-2,2'-dimethyl-1,1'-(oxydiethyl-ene)bis-(1H-benzimidazole)-κN:N]bis-[bis-(4-methoxy-benzoato-κO,O')cadmium(II)].
2010 Mar 20
New alternatives to cosmetics preservation.
2010 Mar-Apr
Bis[μ-2,2'-dimethyl-1,1'-(3-oxapentane-1,5-di-yl)di-1H-benzimidazole-κN:N]bis-[bis-(4-meth-oxy-benzoato)-κO;κO,O'-cobalt(II)].
2010 Nov 13
2,5-Bis(4-meth-oxy-phen-yl)-1,3,4-oxadiazole.
2010 Nov 6
Patents

Sample Use Guides

In Vitro Use Guide
4-methoxy-benzoic acid inhibited β-carbonic anhydrase (EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) with IC50 value of 9.9 nM.
Name Type Language
P-ANISIC ACID
INCI   MI  
INCI  
Official Name English
4-ANISIC ACID
Systematic Name English
DRACONIC ACID
Common Name English
P-ANISIC ACID [INCI]
Common Name English
NSC-32742
Code English
P-ANISIC ACID [MI]
Common Name English
4-METHOXYBENZOIC ACID [FHFI]
Code English
4-METHOXYBENZOIC ACID
FHFI  
Systematic Name English
FEMA NO. 3945
Code English
Classification Tree Code System Code
JECFA EVALUATION 4-METHOXYBENZOIC ACID
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
Code System Code Type Description
CAS
100-09-4
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY
RXCUI
1426595
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY RxNorm
PUBCHEM
7478
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY SWITZERF
EPA CompTox
100-09-4
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY
MERCK INDEX
M1929
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY Merck Index
ECHA (EC/EINECS)
202-818-5
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY
WIKIPEDIA
P-ANISIC ACID
Created by admin on Tue Mar 06 11:29:38 UTC 2018 , Edited by admin on Tue Mar 06 11:29:38 UTC 2018
PRIMARY