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Details

Stereochemistry ACHIRAL
Molecular Formula C21H19ClN4O2
Molecular Weight 394.854
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SSR-180575

SMILES

CN(C)C(=O)CC1=NN(C2=CC=CC=C2)C(=O)C3=C1C4=CC=C(Cl)C=C4N3C

InChI

InChIKey=HJSQVJOROCIILI-UHFFFAOYSA-N
InChI=1S/C21H19ClN4O2/c1-24(2)18(27)12-16-19-15-10-9-13(22)11-17(15)25(3)20(19)21(28)26(23-16)14-7-5-4-6-8-14/h4-11H,12H2,1-3H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.
2002 Jun
Patents

Patents

Name Type Language
SSR-180575
Code English
7-CHLORO-4,5-DIHYDRO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3H-PYRIDAZINO(4,5-B)INDOLE-1-ACETAMIDE
Systematic Name English
3H-PYRIDAZINO(4,5-B)INDOLE-1-ACETAMIDE, 7-CHLORO-4,5-DIHYDRO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-
Systematic Name English
Code System Code Type Description
PUBCHEM
9930560
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY
FDA UNII
4K8W47WK2L
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY
SMS_ID
300000042533
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY
WIKIPEDIA
SSR-180,575
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY SSR-180,575 is a drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action.
CAS
220448-02-2
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY
EPA CompTox
DTXSID10433007
Created by admin on Fri Dec 15 16:21:30 GMT 2023 , Edited by admin on Fri Dec 15 16:21:30 GMT 2023
PRIMARY