Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H19ClN4O2 |
| Molecular Weight | 394.854 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C(=O)CC1=NN(C2=CC=CC=C2)C(=O)C3=C1C4=C(C=C(Cl)C=C4)N3C
InChI
InChIKey=HJSQVJOROCIILI-UHFFFAOYSA-N
InChI=1S/C21H19ClN4O2/c1-24(2)18(27)12-16-19-15-10-9-13(22)11-17(15)25(3)20(19)21(28)26(23-16)14-7-5-4-6-8-14/h4-11H,12H2,1-3H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development. | 2006-06 |
|
| Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion. | 2003-09 |
|
| SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair. | 2002-06 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
9930560
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY | |||
|
4K8W47WK2L
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY | |||
|
300000042533
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY | |||
|
SSR-180,575
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY | SSR-180,575 is a drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It has been shown to have neuroprotective and cardioprotective effects and to stimulate steroidogenesis of pregnenolone in the brain, which may be linked to its neuroprotective action. | ||
|
220448-02-2
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY | |||
|
DTXSID10433007
Created by
admin on Mon Mar 31 18:25:59 GMT 2025 , Edited by admin on Mon Mar 31 18:25:59 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
