Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C100H156N34O22S.6C2H4O2 |
| Molecular Weight | 2578.9 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 15 / 15 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC4=CNC5=C4C=CC=C5)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N6CCC[C@H]6C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
InChI
InChIKey=LYPRXAFXZWKCBL-XDFLZOAHSA-N
InChI=1S/C100H156N34O22S.6C2H4O2/c1-56(2)82(96(155)118-53-79(138)120-65(23-9-12-37-101)85(144)124-66(24-10-13-38-102)87(146)125-67(27-16-41-114-99(108)109)86(145)123-64(83(105)142)26-15-40-113-98(106)107)133-95(154)77-29-18-43-134(77)97(156)71(25-11-14-39-103)121-80(139)52-117-84(143)74(47-59-50-116-63-22-8-7-21-62(59)63)130-88(147)68(28-17-42-115-100(110)111)126-92(151)73(45-57-19-5-4-6-20-57)129-93(152)75(48-60-51-112-55-119-60)131-89(148)69(34-35-81(140)141)127-90(149)70(36-44-157-3)128-94(153)76(54-135)132-91(150)72(122-78(137)49-104)46-58-30-32-61(136)33-31-58;6*1-2(3)4/h4-8,19-22,30-33,50-51,55-56,64-77,82,116,135-136H,9-18,23-29,34-49,52-54,101-104H2,1-3H3,(H2,105,142)(H,112,119)(H,117,143)(H,118,155)(H,120,138)(H,121,139)(H,122,137)(H,123,145)(H,124,144)(H,125,146)(H,126,151)(H,127,149)(H,128,153)(H,129,152)(H,130,147)(H,131,148)(H,132,150)(H,133,154)(H,140,141)(H4,106,107,113)(H4,108,109,114)(H4,110,111,115);6*1H3,(H,3,4)/t64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,82-;;;;;;/m0....../s1
Giractide is a polypeptide hormone corresponding to the first eighteen amino acid residues of corticotropin in which the 1-serine is replaced by glycine. Giractide acts through the stimulation of cell surface the adrenocorticotropic hormone (ACTH) receptors, which are primarily located on the adrenocortical cells. Giractide stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). Giractide has been studied in animal models to stimulate glucocorticoid production.
Approval Year
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m5733
Created by
admin on Sat Dec 16 05:40:35 GMT 2023 , Edited by admin on Sat Dec 16 05:40:35 GMT 2023
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PRIMARY | Merck Index | ||
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4E4Z2VCU8W
Created by
admin on Sat Dec 16 05:40:35 GMT 2023 , Edited by admin on Sat Dec 16 05:40:35 GMT 2023
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29365-11-5
Created by
admin on Sat Dec 16 05:40:35 GMT 2023 , Edited by admin on Sat Dec 16 05:40:35 GMT 2023
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72941539
Created by
admin on Sat Dec 16 05:40:35 GMT 2023 , Edited by admin on Sat Dec 16 05:40:35 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
