U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C30H34N8O3
Molecular Weight 554.6428
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LAZERTINIB

SMILES

COC1=C(NC2=NC=CC(=N2)N3C=C(CN(C)C)C(=N3)C4=CC=CC=C4)C=C(NC(=O)C=C)C(=C1)N5CCOCC5

InChI

InChIKey=RRMJMHOQSALEJJ-UHFFFAOYSA-N
InChI=1S/C30H34N8O3/c1-5-28(39)32-23-17-24(26(40-4)18-25(23)37-13-15-41-16-14-37)33-30-31-12-11-27(34-30)38-20-22(19-36(2)3)29(35-38)21-9-7-6-8-10-21/h5-12,17-18,20H,1,13-16,19H2,2-4H3,(H,32,39)(H,31,33,34)

HIDE SMILES / InChI

Approval Year

Name Type Language
LAZERTINIB
INN   USAN  
Official Name English
lazertinib [INN]
Common Name English
YH-25448
Code English
YH25448
Code English
C-18112003-G
Code English
GNS-1480
Code English
2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-
Systematic Name English
N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE
Systematic Name English
Lazertinib [WHO-DD]
Common Name English
LAZERTINIB [USAN]
Common Name English
GNS1480
Code English
JNJ-73841937-AAA
Code English
Classification Tree Code System Code
NCI_THESAURUS C129825
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
NCI_THESAURUS C2167
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
Code System Code Type Description
CAS
1903008-80-9
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
NCI_THESAURUS
C148147
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
USAN
HI-167
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
SMS_ID
300000000788
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
INN
10587
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
FDA UNII
4A2Y23XK11
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY
PUBCHEM
121269225
Created by admin on Sat Dec 16 13:40:36 GMT 2023 , Edited by admin on Sat Dec 16 13:40:36 GMT 2023
PRIMARY