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Details

Stereochemistry ACHIRAL
Molecular Formula FO3P
Molecular Weight 97.9704
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of MONOFLUOROPHOSPHATE ION

SMILES

FP(=O)([O-])[O-]

InChI

InChIKey=DWYMPOCYEZONEA-UHFFFAOYSA-L
InChI=1S/FH2O3P/c1-5(2,3)4/h(H2,2,3,4)/p-2

HIDE SMILES / InChI
Monofluorophosphate (MFP) is an anion, which is a phosphate group with one oxygen atom substituted with a fluorine atom. Sodium Monofluorophosphate is intended to be used by both petitioners in food supplements as a source of fluoride in the forms of multi-vitamin, multi-mineral supplements, solid tablets or tablets dispersible in liquid. The toxic effects of Monofluorophosphate are attributable to the fluoride ion released by the in vivo hydrolysis of the parent compound. The Monofluorophosphate ion appears to play no role. The acute toxicity of Monofluorophosphate is somewhat less than that of NaF, due to the lesser availability of fluoride in the short term from Monofluorophosphate. In the long term, Monofluorophosphate produces virtually the same picture of renal effects and skeletal storage of fluoride as does NaF. Sodium Monofluorophosphate dissociates into sodium and Monofluorophosphate ions in the intestinal tract, the latter being absorbed mainly in the upper small intestine.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
3.4 mM [Ki]
69.0 µM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
AMERFRESH

Approved Use

helps potect against cavities.

Launch Date

8.2045442E11
Patents

Patents

Name Type Language
MONOFLUOROPHOSPHATE ION
Common Name English
Code System Code Type Description
RXCUI
1546445
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
EVMPD
SUB31804
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
DRUG BANK
DB02348
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
RXCUI
52885
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
ALTERNATIVE
FDA UNII
4964UZ79MI
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
CAS
15181-43-8
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
EPA CompTox
15181-43-8
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY
PUBCHEM
65241
Created by admin on Sat Jun 26 13:52:04 UTC 2021 , Edited by admin on Sat Jun 26 13:52:04 UTC 2021
PRIMARY