TECHNETIUM TC-99M SUCCIMER

First approved in 1973

Details

Stereochemistry	ABSOLUTE
Molecular Formula	2C4H6O4S2.OTc
Molecular Weight	479.342
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	3

SHOW SMILES / InChI

Structure Search

SMILES

O=[99Tc+3].OC(=O)[C@@H](S)[C@@H](S)C(O)=O.OC(=O)[C@@H](S)[C@@H](S)C(O)=O

InChI

InChIKey=VKIPEVJBUHKZRV-RSQQSNPGSA-N

InChI=1S/2C4H6O4S2.O.Tc/c2*5-3(6)1(9)2(10)4(7)8;;/h2*1-2,9-10H,(H,5,6)(H,7,8);;/q;;;+3/t2*1-,2+;;/i;;;1+1

HIDE SMILES / InChI

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

TECHNETIUM TC-99M SUCCIMER

Common Name

English

TECHNETIUM (99MTC) PENTAVALENT SUCCIMER

Common Name

English

TECHNETIUM-99M-(V)-DIMERCAPTOSUCCINIC ACID

Common Name

English

NEPHROSCAN

Brand Name

English

TECHNETIUM-99-DMSA

Common Name

English

TECHNETIUM TC-99M SUCCIMER KIT

Common Name

English

TECHNETIUM TC 99M SUCCIMER

Common Name

English

TECHNETIUM-99 DIMERCAPTOSUCCINATE

Common Name

English

99MTC-DMSA

Common Name

English

TECHNETIUM TC 99M SUCCIMER [USP IMPURITY]

Common Name

English

TC-99M DMSA

Common Name

English

BUTANEDIOIC ACID, 2,3-DIMERCAPTO-, TECHNETIUM-99TC SALT

Common Name

English

PENTAVALENT TECHNETIUM-99M-DIMERCAPTOSUCCINIC

Common Name

English

TECHNETIUM (SUP 99M)TC) DIMERCAPTOSUCCINIC ACID

Common Name

English

TECHNETIUM TC 99M DIMERCAPTOSUCCINIC ACID

Common Name

English

TECHNETIUM TC-99M SUCCIMER KIT [ORANGE BOOK]

Common Name

English

Technetium tc 99m succimer [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

V09IA03