U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H32O3
Molecular Weight 320.4663
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 4
Charge 0

SHOW SMILES / InChI
Structure of 5-HETE

SMILES

CCCCC\C=C/C\C=C/C\C=C/C=C/[C@@H](O)CCCC(O)=O

InChI

InChIKey=KGIJOOYOSFUGPC-JGKLHWIESA-N
InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Vitamin E modulates the lipoxygenation of arachidonic acid in leukocytes.
1980 Nov 13
Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.
1983 Aug 1
Quantitative changes of hydroxyacid formation during platelet-neutrophil interaction.
1993 Mar
A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors.
2008 Apr 14
Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model.
2010 Mar 15
5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism.
2016 Feb
Name Type Language
5-HETE
MI  
Common Name English
5-HYDROXYEICOSATETRAENOIC ACID
Systematic Name English
5-HETE [MI]
Common Name English
5-HETE, (S)-
Common Name English
5(S)-HYDROXYEICOSATETRAENOIC ACID
Common Name English
6,8,11,14-EICOSATETRAENOIC ACID, 5-HYDROXY-, (5S,6E,8Z,11Z,14Z)-
Systematic Name English
5-HYDROXY-6,8,11,14-EICOSATETRAENOIC ACID
Systematic Name English
5-L-HYDROXY-6,8,11,14-EICOSATETRAENOIC ACID
Common Name English
5(S)-HYDROXY-6-TRANS-8,11,14-CIS-EICOSATETRAENOIC ACID
Systematic Name English
5(S)-HETE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C463
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID701017281
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
FDA UNII
467RNW8T91
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
NCI_THESAURUS
C558
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
CAS
70608-72-9
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
MERCK INDEX
m5979
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY Merck Index
CHEBI
28209
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
WIKIPEDIA
5-Hydroxyeicosatetraenoic acid
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY
PUBCHEM
5280733
Created by admin on Sat Dec 16 08:26:17 GMT 2023 , Edited by admin on Sat Dec 16 08:26:17 GMT 2023
PRIMARY