Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H6N2O |
| Molecular Weight | 146.146 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1NN=CC2=C1C=CC=C2
InChI
InChIKey=IJAPPYDYQCXOEF-UHFFFAOYSA-N
InChI=1S/C8H6N2O/c11-8-7-4-2-1-3-6(7)5-9-10-8/h1-5H,(H,10,11)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Novel phthalazinone and benzoxazinone containing thiazolidinediones as antidiabetic and hypolipidemic agents. | 2001 Jul-Aug |
|
| Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones. | 2002 Jun 6 |
|
| Synthesis and structural characterization of 1-(D-glycosyloxy)phthalazines. | 2003 Oct 31 |
|
| Enzymatic oxidation of phthalazine with guinea pig liver aldehyde oxidase and liver slices: inhibition by isovanillin. | 2004 |
|
| Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities. | 2004 Dec |
|
| Some pyridazinone and phthalazinone derivatives and their vasodilator activities. | 2004 Jan |
|
| Human liver aldehyde oxidase: inhibition by 239 drugs. | 2004 Jan |
|
| Anti-HIV activity of stilbene-related heterocyclic compounds. | 2006 Aug 1 |
|
| Microwave-assisted cyclic amidine synthesis using TiCl4. | 2006 Aug 21 |
|
| Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase. | 2006 Feb 15 |
|
| Synthesis and molluscicidal activity of some 1,3,4-triaryl-5-chloropyrazole, pyrano[2,3-c]pyrazole, pyrazolylphthalazine and pyrano[2,3-d]thiazole derivatives. | 2006 Jun |
|
| Azamerone, a terpenoid phthalazinone from a marine-derived bacterium related to the genus Streptomyces (Actinomycetales). | 2006 Jun 8 |
|
| Vasorelaxant activity of phthalazinones and related compounds. | 2006 May 15 |
|
| Design and syntheses of novel phthalazin-1(2H)-one derivatives as acetohydroxyacid synthase inhibitors. | 2006 Nov 29 |
|
| Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability. | 2007 Oct |
|
| Regioselective synthesis of N-aminoisoindolones and mono-N- and di-N,N'-substituted phthalazones utilizing hydrazine nucleophiles in a palladium-catalyzed three-component cascade process. | 2008 Nov 7 |
|
| Synthesis and biological evaluation of novel phthalazinone derivatives as topically active phosphodiesterase 4 inhibitors. | 2009 Oct 1 |
|
| Modifying a proton conductive membrane by embedding a "barrier". | 2010 Oct 21 |
|
| Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis. | 2010 Sep 7 |
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52567
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SUBSTANCE RECORD
