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Details

Stereochemistry ACHIRAL
Molecular Formula C4H10O2S2
Molecular Weight 154.251
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-HYDROXYETHYL DISULFIDE

SMILES

OCCSSCCO

InChI

InChIKey=KYNFOMQIXZUKRK-UHFFFAOYSA-N
InChI=1S/C4H10O2S2/c5-1-3-7-8-4-2-6/h5-6H,1-4H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Plasmoredoxin, a novel redox-active protein unique for malarial parasites.
2003 Mar
Improved resolution of the human adipose tissue proteome at alkaline and wide range pH by the addition of hydroxyethyl disulfide.
2004 Feb
Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).
2004 Jan
Facile synthesis of chlorophyll analog possessing a disulfide bond and formation of self-assembled monolayer on gold surface.
2004 Jan 23
Analyzing alkaline proteins in human colon crypt proteome.
2004 Jul-Aug
Fishing of beta-amylase with a SAM of alpha-cyclodextrin-poly- (ethylene glycol) conjugate.
2004 Nov 15
A simplified 2-D electrophoresis protocol with the aid of an organic disulfide.
2005 Aug
Expression and oxidative stress tolerance studies of glutaredoxin from cyanobacterium Synechocystis sp. PCC 6803 in Escherichia coli.
2005 Jul
A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.
2005 Jul 1
Optimised two-dimensional electrophoresis procedures for the protein characterisation of structural tissues.
2005 May
Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein.
2006 Feb 21
Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.
2006 Mar 8
Proteomic analysis of human plasma proteins by two-dimensional gel electrophoresis and by antibody arrays following depletion of high-abundance proteins.
2007
The two-domain structure of 5'-adenylylsulfate (APS) reductase from Enteromorpha intestinalis is a requirement for efficient APS reductase activity.
2007 Jan 16
Combined cup loading, bis(2-hydroxyethyl) disulfide, and protein precipitation protocols to improve the alkaline proteome of Lactobacillus hilgardii.
2007 May
Uptake and reduction of alpha-lipoic acid by human erythrocytes.
2007 Oct
Plant protein isolation and stabilization for enhanced resolution of two-dimensional polyacrylamide gel electrophoresis.
2008 Aug 15
Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into iron-sulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins.
2008 Feb 5
Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1.
2008 Jan
Selenoglutaredoxin as a glutathione peroxidase mimic.
2008 Jul 2
Multiple stressor-induced proteome responses of Escherichia coli BL21(DE3).
2008 May
Water-induced hydrophobicity of soy protein materials containing 2,2-diphenyl-2-hydroxyethanoic acid.
2008 Sep
Trypanosoma cruzi alkaline 2-DE: Optimization and application to comparative proteome analysis of flagellate life stages.
2008 Sep 8
New insights into the biodegradation of thiodiglycol, the hydrolysis product of Yperite (sulfur mustard gas).
2009 Apr
Improved resolution in the acidic and basic region of 2-DE of insect antennae proteins using hydroxyethyl disulfide.
2009 Aug
Human G-CSF synthesis using stress-responsive bacterial proteins.
2009 Jul
Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase.
2009 Jul 21
Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP.
2009 Jun 26
Cloning, expression, and characterization of an enzyme possessing both glutaredoxin and dehydroascorbate reductase activity from Taiwanofungus camphorata.
2009 Nov 11
Proximity-based protein thiol oxidation by H2O2-scavenging peroxidases.
2009 Nov 13
2-DE analysis indicates that Acinetobacter baumannii displays a robust and versatile metabolism.
2009 Sep 28
An update on the mouse liver proteome.
2009 Sep 8
Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci).
2010
Glutathione-mediated biodegradable polyurethanes derived from L-arabinitol.
2010 Jan 11
pO(2)-dependent NO production determines OPPC activity in macrophages.
2010 Jan 15
Expression and characterization of three new glutathione transferases, an epsilon (AcGSTE2-2), omega (AcGSTO1-1), and theta (AcGSTT1-1) from Anopheles cracens (Diptera: Culicidae), a major Thai malaria vector.
2010 Mar
Amyloid-like aggregates of the yeast prion protein ure2 enter vertebrate cells by specific endocytotic pathways and induce apoptosis.
2010 Sep 2
Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE.
2010 Sep 22
A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells.
2013 Feb
Patents
Name Type Language
2-HYDROXYETHYL DISULFIDE
Systematic Name English
2-MERCAPTOETHANOL DISULFIDE
Systematic Name English
NSC-33920
Code English
2,2'-DITHIOBISETHANOL
Systematic Name English
ETHANOL, 2,2'-DITHIOBIS-
Systematic Name English
2-HYDROXYETHANE DISULFIDE
Common Name English
.BETA.-HYDROXYETHYL DISULFIDE
Systematic Name English
HYDROXYETHYL DISULPHIDE, 2-
Systematic Name English
ETHANOL, 2,2'-DITHIODI-
Systematic Name English
3,4-DITHIA-1,6-HEXANEDIOL
Systematic Name English
2,2'-DITHIODIETHANOL
Systematic Name English
Code System Code Type Description
DRUG BANK
DB02486
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
ECHA (EC/EINECS)
217-576-6
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
CAS
1892-29-1
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
EPA CompTox
DTXSID4044404
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
NSC
33920
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
FDA UNII
45543L74BS
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
CHEBI
43136
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY
PUBCHEM
15906
Created by admin on Fri Dec 15 19:00:21 GMT 2023 , Edited by admin on Fri Dec 15 19:00:21 GMT 2023
PRIMARY