Broussonin A

COC1=CC=C(CCCC2=CC=C(O)C=C2)C(O)=C1

InChIKey=MSNVBURPCQDLEP-UHFFFAOYSA-N

InChI=1S/C16H18O3/c1-19-15-10-7-13(16(18)11-15)4-2-3-12-5-8-14(17)9-6-12/h5-11,17-18H,2-4H2,1H3

Targets

Primary Target	Pharmacology	Condition	Potency
nitric oxide production involved in inflammatory response 17 Target ID: GO:0002537 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24827684	Inhibitor 8504		3.7 µM [IC50]
negative regulation of NF-kappaB transcription factor activity 1 Target ID: GO:0032088 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24827684	Modulator 846

PubMed

Title	Date	PubMed
Suppression of inducible nitric oxide synthase expression by nyasol and broussonin A, two phenolic compounds from Anemarrhena asphodeloides, through NF-κB transcriptional regulation in vitro and in vivo.	2014-05	24827684

Name

Type

Language

2-[3-(4-Hydroxyphenyl)propyl]-5-methoxyphenol

Preferred Name

English

Broussonin A

Common Name

English

Phenol, 2-[3-(4-hydroxyphenyl)propyl]-5-methoxy-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID901317996

Created by admin on Wed Apr 02 06:48:13 GMT 2025 , Edited by admin on Wed Apr 02 06:48:13 GMT 2025

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FDA UNII

44SF3SS9W7

Created by admin on Wed Apr 02 06:48:13 GMT 2025 , Edited by admin on Wed Apr 02 06:48:13 GMT 2025

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CAS

73731-87-0

Created by admin on Wed Apr 02 06:48:13 GMT 2025 , Edited by admin on Wed Apr 02 06:48:13 GMT 2025

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PUBCHEM

5315502

Created by admin on Wed Apr 02 06:48:13 GMT 2025 , Edited by admin on Wed Apr 02 06:48:13 GMT 2025

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SUBSTANCE RECORD


					44SF3SS9W7