MENTHYL SALICYLATE, (±)-

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H24O3
Molecular Weight	276.3707
Optical Activity	( + / - )
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C2=CC=CC=C2O

InChI

InChIKey=SJOXEWUZWQYCGL-DVOMOZLQSA-N

InChI=1S/C17H24O3/c1-11(2)13-9-8-12(3)10-16(13)20-17(19)14-6-4-5-7-15(14)18/h4-7,11-13,16,18H,8-10H2,1-3H3/t12-,13+,16-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=50d6008a-43c6-4cfd-8e56-e29e66097d6c&type=display

MENTHYL SALICYLATE is an active component of COLD SPOT POINT RELIEF gel, which is indicated for temporary relief of minor aches and pains of the muscles and joints associated with simple backache, arthritis, bruises, strains and/or sprains.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pains of the muscles and joints 1 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=50d6008a-43c6-4cfd-8e56-e29e66097d6c	Palliative		Approved 8583	SALONPAS Approved Use COLD SPOT POINT RELIEF is indicated for temporary relief of minor aches and pains of the muscles and joints associated with simple backache, arthritis, bruises, strains and/or sprains. Launch Date 2008

Overview

CYP3A4	CYP2C9	CYP2D6	hERG
inhibitor 2252 inducer 1087	inhibitor 2438	inhibitor 2507

OverviewOther

Other Inhibitor	Other Substrate	Other Inducer
CYP19A1 429	P-gp 2052

Drug as perpetrator

Target	Modality	Activity
CYP19A1 430	inhibitor 4027 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 13.0	no
CYP2C9 2497	inhibitor 4027 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 18.0	no
CYP2D6 2546	inhibitor 4027 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 18.0	no
CYP3A4 2633	inducer 1966 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 17.0	no
CYP3A4 2633	inhibitor 4027 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 18.0	no

Drug as victim

Target	Modality	Activity	Metabolite	Clinical evidence
P-gp 2052	substrate 4014 Sources: https://pubchem.ncbi.nlm.nih.gov/compound/20055232#section=BioAssay-Results Page: 16 \| 17	no

Name

Type

Language

MENTHYL SALICYLATE, (±)-

Systematic Name

English

MENTHYL SALICYLATE

Preferred Name

English

Menthyl salicylate [WHO-DD]

Common Name

English

BENZOIC ACID, 2-HYDROXY-, (1R,2S,5R)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXYL ESTER, REL-

Common Name

English

MENTHYL SALICYLATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C851